Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine consolidates the latest information on functional genomics and chemical biology approaches that are used to study and control the fate of stem cells.

Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine covers:

• The use of both embryonic and adult stem cells
• A vast array of technologies, including: genome-wide expression analysis, functional genomic profiling with arrayed cDNA and RNAi expression libraries, informatics, chemical genomics, mass spectrometry, and proteomics
• The applications of advanced technologies in various areas of stem cell biology, encompassing: self-renewal, differentiation, and reprogramming of different types of embryonic and adult stem cells, as well as regeneration in model organisms
• Technological tools for studying the biology of stem cells

Contents

1. Embryonic Stem Cells
2. Adult Stem Cells
3. Genome-wide expression analysis technologies
4. Genomic cDNA and RNAi Functional Profiling and its Potential Application to the Study of Mammalian Stem Cells
5. Chemical Technologies: Probing Biology with Small Molecules
6. Protein Characterization by Biological Mass Spectrometry
7. Large scale genomic analysis of stem cell populations
8. Exploring stem cell biology with small molecules and functional genomics
9. Regeneration Screens in Model Organisms
10. Proteomics in stem cells

Index

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