Clinical Endocrine Oncology provides specific and detailed guidance on the basic, clinical, investigative and therapeutic processes required for the thorough evaluation of a patient with a tumor in an endocrine organ.

The eighty-four chapters are arranged in seven parts:

• Endocrine Oncology and Therapeutic Options
• Thyroid and Parathyroid Tumors
• Pituitary and Hypothalamic Lesions
• Adrenal and Gonadal Tumors
• Neuroendocrine Tumors and the Clinical Syndromes
• Medical Syndromes and Endocrine Neoplasia
• Endocrine-responsive Tumors and Female Reproductive Hormone Therapy

Clinical Endocrine Oncology will be an invaluable resource for all those working in the field, including endocrinologists, medical oncologists, surgeons, radiation therapists, interventional radiologists, specialist nurses, and clinical scientists.

Contents

Endocrine Oncology and Therapeutic Options

1. Structure and Development of the Endocrine System
2. Epidemiology of Endocrine Tumors
3. Inherited Cancers, Genes and Chromosomes
4. Hormones, Growth Factors and Tumor Growth
5. Genetic Counselling and Clinical Cancer Genetics
6. Prospects for Gene Therapy for Endocrine Malignancies
7. Tumor Targeting
8. Techniques in Radiation Medicine
9. Interventional Radiology
10. Surgical Management of Endocrine Tumors
11. Endocrine Tumor Markers
12. General Management of Cancer Patients

Thyroid and Parathyroid Tumors

13. The Assessment of Thyroid Neoplasia.
14. Thyroid and Parathyroid Imaging.
15. Pathogenesis of Thyroid Cancer.
16. Papillary Thyroid Cancer.
17. Follicular Thyroid Carcinoma.
18. Anaplastic Thyroid Carcinoma.
19. Thyroid Lymphoma.
20. Radiation Induced Thyroid Tumors.
21. Parathyroid Adenomas and Hyperplasia.
22. Parathyroid Carcinoma

Pituitary and Hypothalamic Lesions

23. Molecular Pathogenesis of Pituitary Adenomas.
24. Functional Assessment of the Pituitary.
25. Imaging of the Pituitary and Hypothalamus.
26. Pathology of Tumors of the Pituitary.
27. Surgery for Pituitary Tumors.
28. Pituitary Radiotherapy.
29. Prolactinomas.
30. Acromegaly.
31. Cushing's Disease.
32. Non Functioning Pituitary Adenomas and Gonadotropinomas.
33. Thyrotropinomas.
34. Pituitary Carcinoma.
35. Pituitary Incidentalomas.
36. Craniopharyngioma.
37. Benign Cysts: Rathke's Cysts, Mucoceles, Arachnoid Cysts, and Dermoid and Epidermoid Cysts.
38. Hypothalamic Hamartomas and Gangliocytomas.
39. Cranial Ependymoma.
40. Perisellar Tumors Including Chordoma, Optic Nerve Glioma, Meningioma, Hemangiopericytoma and Glomus Tumors.
41. Pineal Tumors: Germinomas and Non Germinomatous Germ Cell Tumors.
42. Cavernous Sinus Hemangiomas.
43. Langerhans' Cell Histiocytosis.
44. Pituitary and Hypothalamic Sarcoidosis

Adrenal and Gonadal Tumors

45. Imaging of the Adrenal Glands.
46. Pheochromocytoma.
47. Peripheral Neuroblastic Tumors.
48. Primary Hyperaldosteronism.
49. Adrenal Causes of Cushing's Syndrome.
50. Adrenal Incidentalomas.
51. Androgen Secreting Tumors.
52. Functional Ovarian Tumors.
53. Endocrine Aspects of Ovarian Cancer.
54. Testicular Germ-cell Cancers.
55. Neoplasia and Intersex States.
56. Gestational Trophoblastic Neoplasia

Neuroendocrine Tumors and the Clinical Syndromes

57. Classification of Neuroendocrine Tumors.
58. Imaging of Gastrointestinal Neuroendocrine Tumors.
59. Insulinomas and Hypoglycemia.
60. Gastrinoma (Zollinger-Ellison Syndrome).
61. VIPomas.
62. Glucagonomas.
63. Somatostatinoma.
64. Lung and Thymic Neuroendocrine Tumors.
65. Carcinoid Syndrome.
66. Appendiceal and Hindgut Carcinoids.
67. Chemotherapy for Neuroendocrine Tumors

Medical Syndromes and Endocrine Neoplasia

68. Multiple Endocrine Neoplasia Type 1 (MEN 1).
69. Medullary Thyroid Carcinoma and Associated Multiple Endocrine Neoplasia Type 2.
70. von Hippel-Lindau Disease.
71. Neurofibromatosis Type 1.
72. Carney Complex.
73. McCune-Albright Syndrome.
74. Cowden Syndrome.
75. Paraneoplastic Syndromes.
76. Syndrome of Inappropriate Antidiuretic Hormone Secretion.
77. Hypercalcemia of Malignancy.
78. Syndrome of Ectopic ACTH Secretion.
79. Insulin-like Growth Factors and Tumor Hypoglycemia.
80. Metastatic and Other Extraneous Neoplasms in Endocrine Organs.
81. Endocrine Late-Effects of Cancer Therapy

Endocrine-responsive Tumors and the Effects of Female Reproductive Hormone Therapy

82. Endocrine-responsive Tumors: Prostate Cancer.
83. Endocrine Therapy in Breast Cancer Management.
84. Female Reproductive Hormone Therapy: Risks and Benefits

Index

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