Cancer Research Book from C.H.I.P.S.

Cancer and the Search for Selective Biochemical Inhibitors
Second edition
by E. J. Hoffman

Cancer and the Search for Selective Biochemical Inhibitors, Second Edition includes coverage of the link between concepts and practices of alternative and conventional medicine. It compares complementary, alternative, and integrative treatments with chemotherapy and other more traditional treatments.


  • Reviews the wealth of information available from a wide range of sources about anticancer plants and herbs
  • Explores bodily biochemical processes, how enzymes and enzyme inhibitors are involved, and how this knowledge assists in the treatment of cancer
  • Examines how conventional chemotherapy merges with concepts of alternative and complementary medicine
  • Covers the biochemistry of cancer and how this knowledge can aid patients and practitioners in treatment
  • Includes some of the more unusual esoterica about cancer and its causes, treatment, and cures
  • Discusses cancerous stem cells and the search for natural and synthetic biochemicals and chemicals that will inhibit the key enzyme involved, namely tyrosine kinase

This book examines anticancer plant substances and other alternatives such as Vitamin C, essiac tea, shark cartilage, and cat's claw. The book also addresses the problem of determining selective and non-toxic enzyme inhibitors for cancer cell metabolic pathways.



  • The Nutritional Brouhaha
  • The Ponderables of Biochemistry
  • Troubles of Mind
  • What Seems to Work
  • Scourges in the Making
  • Remedies in Nature
  • Poisons in Nature
  • From the Ordinary to the Bizarre
  • The Environment, Naturally and Not So Naturally
  • Where to from Here?

Cancer Origins and Characteristics

  • Cancer Formation and Oncogenes
  • Types of Cancers
  • Pleomorphism
  • Viral or Microbial Origins and Treatments
  • Viruses and Lysogeny
  • Viruses and Subviruses
  • Antiviral Agents
  • Immune Reactions
  • Vaccines

Biochemical Insights

  • The Warburg Cancer Theory
  • Cell Metabolism
  • Enzyme-Catalyzed Metabolic Pathways
  • Overall Glycolytic Conversions
  • Cancer Cell Metabolism vs. Normal Cell Metabolism
  • Selective Biochemical Inhibitors
  • The Tricarboxylic Cycle and Respiration
  • Vitamins and Hormones as Inhibitors or Promoters
  • Chemotherapy Drugs as Enzyme Inhibitors
  • More on Folic Acid
  • Enzyme Transformations

Starting at the Genetic Level

  • DNA, RNA, and Protein Synthesis
  • The Ubiquitous Roles of Proteins
  • Genetics as Science
  • Digestive Processes
  • Proteases and Their Inhibitors
  • Protein Degradation Rates
  • The Influence of Antibiotics
  • DNA Replication and Alteration
  • Chemoprevention
  • Commentary

Enzymatic Biochemical Treatment Protocols

  • Enzymes
  • Enzyme Inhibitors
  • Enzyme Inhibition in Modern Medicine
  • Enzyme Inhibitors for Melanoma
  • Diet
  • Dietary Extremes
  • Iron in the Diet
  • Garlic and Allicin and Other Sulfur-Containing Compounds as Anticancer Agents
  • Aberrations
  • Immunity
  • Cancer Markers
  • High-Tech vs. Low-Tech
  • Footdragging on Using Enzyme Inhibitors

The Alternative Scene

  • An Introduction to Alternatives
  • Some Alternatives, Information Sources, and Assessments
  • More About the Plant World
  • Poisonous and Medicinal Plants
  • Plants and Herbs as Agents Against Other Diseases
  • Selectivity
  • The Nitrogen Connection and Immunotherapy
  • Alkaloids and Bioactivity
  • Microorganisms and Immunity
  • In Short Summary

Surveying Anticancer Plant Substances

  • Status of Plants Against Cancer
  • Laetrile Quandaries
  • Plants of the American West and Southwest
  • Chaparral
  • Other Plants and Herbs
  • South Africa
  • China
  • Soviet Union
  • Mexico
  • Australia
  • Egypt and Israel
  • United States
  • Great Britain
  • Still Other Options
  • Mystique Surrounding Cancer Cures
  • Miscellaneous
  • Neo Tropica
  • Some Further Alternatives
  • Successes vs. Failures
  • Biological Response

On Overcoming the Intractability of Cancer

  • Cell Resistance and Some Consequences
  • Alternative Treatment: The Status Quo
  • Controversies
  • Heroic Efforts
  • More about Compound-X and the Like
  • An Update on News and Views
  • Cancer Directives
  • The Continuing Legacy of Wayne Martin and Compatriots
  • More of the Latest on Alternatives
  • Magnesium
  • Peripherals
  • Subviral Agents: Prions
  • More on DNA
  • More on Diet
  • The Navajo and Cancer

Cancer Esoterica

  • The Morphism of Cancer Cells
  • Electromagnetic Phenomena and Cancer
  • Some Inexplicables
  • Metastasis, Resistance, and Aberrations
  • More on Immunity
  • Bioterrorism
  • The Halogens and Cause and Cure
  • The Effect of Toxins in the Environment
  • More on Chemotherapy, Alkaloids, and Other Plant Biochemicals
  • Recourses
  • Circling the Wagons
  • More on Genetic Modification or Engineering
  • Vaccination and Cancer
  • Telomerase Inhibitors
  • Histone Diacetylase Inhibitors
  • Markers for Monitoring Cancer Growth and Remission
  • Moral and Ethical Quandaries

The Inhibition of Cancerous Stem Cells

  • The Subject of Stem Cells and Cancer
  • Cancerous Stem Cells and Immunity
  • Inhibition of Cancerous Stem Cells
  • Tyrosine Kinase
  • Plant Sources for Tyrosine Kinase Inhibitors


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Cancer and the Search for Selective Biochemical Inhibitors
Second edition
by E. J. Hoffman

2007 480 pages $148.95 + shipping
Texas residents please add 6.75 % sales tax

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