Contact Dermatitis 4th edition is an up-dated coverage of every conceivable aspect of the modern-day management of contact dermatitis.

Both irritant and allergic contact dermatitis are covered fully and clearly, special emphasis being given to:

• immunolgical mechanisms
• molecular aspects of sensitizers
• atypical clinical forms
• reactions to medicaments
• occupational and environmental aspects

Several new chapters focus on fragrances, hair dyes, and methods for quantitative risk assessment of allergens and irritants.

Contact Dermatitis also covers:

• epidemiology
• the histopathology and ultrastructure of contact dermatitis
• methods of skin-testing other than patch testing
• skin penetration
• principles of prevention and protection

Legislative regulations on contact allergens and legal aspects of worker’s compensation for occupational dermatitis are dealt with as well as the expanding use of computers in surveillance sytems and practical management of patients. For optimizing the diagnostic approach a wide scale of information is provided on patch test concentration and vehicles, testing with patient´s own materials and a dictionary of contact allergens regarding chemical structures, sources and references.

A CD-ROM is included providing virtually all clinical pictures and the most pertinent diagrams and tables.

Contents

1. Historical Aspects

Part I: Basic Features

2. Mechanisms in Allergic Contact Dermatitis
3. Molecular Aspects of Allergic Contact Dermatitis
4. Mechanisms of Irritant Contact Dermatitis
5. Immediate Contact Reactions
6. Mechanisms of Phototoxic and Photoallergic Reactions

Part II: Pathology

7. Histopathological and Immunohistopathological Features of Irritant and Allergic Contact Dermatitis
8. Ultrastructure of Irritant and Allergic Contact Dermatitis
9. Individual Predisposition to Irritant and Allergic Contact Dermatitis
10. Epidemiology

Part III: Dermatotoxicology

11. Skin Penetration
12. Predictive Tests for Irritants and Allergens and their Use in Quantitative Risk Assessment
13. Allergic Contact Dermatitis in Humans – Experimental and Quantitative Aspects

Part IV: Clinical Features

14. General Aspects
15. Clinical Aspects of Irritant Contact Dermatitis
16. Systemic Contact Dermatitis
17. Phototoxic and Photoallergic Reactions
18. Pigmented Contact Dermatitis and Chemical Depigmentation
19. Hand Eczema
20. Protein Contact Dermatitis
21. Noneczematous Contact Reactions

Part V: Diagnostic Tests

22. Patch Testing
23. Atopy Patch Testing with Aeroallergens and Food Proteins
24. Patch Testing in Adverse Drug Reactions
25. Allergens Exposure Assessment
26. Skin Tests for Immediate Hypersensitivity
27. Photopatch Testing
28. Noninvasive Techniques for Quantification of Contact Dermatitis

Part VI: Allergic Contact Dermatitis Related to Specific Exposures

29. Allergens from the Standard Series
30. Cosmetics and Skin Care Products
31. Allergens of Special Interest
32. Metals
33. Metalworking Fluids
34. Plastic Materials
35. Topical Drugs
36. Dental Materials
37. Clothing
38. Shoes
39. Occupational Contact Dermatitis
40. Health Personnel
41. Plants and Plant Products
42. Pesticides
43. Contact Allergy in Children
44. Prevention and Therapy
45. Legislation
46. International Comparison of Legal Aspects of Worker Compensation for Occupational Contact Dermatitis
47. Computers in the Management of Contact Dermatitis
48. Contact Dermatitis Research Groups
49. Patch Test Concentrations and Vehicles for Testing Contact Allergens
50. Patch Testing with the Patients’ Own Products
51. Dictionary of Contact Allergens: Chemical Structures, Sources and References

Index

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