Dermatology Book from C.H.I.P.S.

Contact Dermatitis
Fourth edition
edited by P. J. Frosch

Contact Dermatitis 4th edition is an up-dated coverage of every conceivable aspect of the modern-day management of contact dermatitis.

Both irritant and allergic contact dermatitis are covered fully and clearly, special emphasis being given to:

  • immunolgical mechanisms
  • molecular aspects of sensitizers
  • atypical clinical forms
  • reactions to medicaments
  • occupational and environmental aspects

Several new chapters focus on fragrances, hair dyes, and methods for quantitative risk assessment of allergens and irritants.

Contact Dermatitis also covers:

  • epidemiology
  • the histopathology and ultrastructure of contact dermatitis
  • methods of skin-testing other than patch testing
  • skin penetration
  • principles of prevention and protection

Legislative regulations on contact allergens and legal aspects of worker’s compensation for occupational dermatitis are dealt with as well as the expanding use of computers in surveillance sytems and practical management of patients. For optimizing the diagnostic approach a wide scale of information is provided on patch test concentration and vehicles, testing with patient´s own materials and a dictionary of contact allergens regarding chemical structures, sources and references.

A CD-ROM is included providing virtually all clinical pictures and the most pertinent diagrams and tables.


  1. Historical Aspects

Part I: Basic Features

  1. Mechanisms in Allergic Contact Dermatitis
  2. Molecular Aspects of Allergic Contact Dermatitis
  3. Mechanisms of Irritant Contact Dermatitis
  4. Immediate Contact Reactions
  5. Mechanisms of Phototoxic and Photoallergic Reactions

Part II: Pathology

  1. Histopathological and Immunohistopathological Features of Irritant and Allergic Contact Dermatitis
  2. Ultrastructure of Irritant and Allergic Contact Dermatitis
  3. Individual Predisposition to Irritant and Allergic Contact Dermatitis
  4. Epidemiology

Part III: Dermatotoxicology

  1. Skin Penetration
  2. Predictive Tests for Irritants and Allergens and their Use in Quantitative Risk Assessment
  3. Allergic Contact Dermatitis in Humans – Experimental and Quantitative Aspects

Part IV: Clinical Features

  1. General Aspects
  2. Clinical Aspects of Irritant Contact Dermatitis
  3. Systemic Contact Dermatitis
  4. Phototoxic and Photoallergic Reactions
  5. Pigmented Contact Dermatitis and Chemical Depigmentation
  6. Hand Eczema
  7. Protein Contact Dermatitis
  8. Noneczematous Contact Reactions

Part V: Diagnostic Tests

  1. Patch Testing
  2. Atopy Patch Testing with Aeroallergens and Food Proteins
  3. Patch Testing in Adverse Drug Reactions
  4. Allergens Exposure Assessment
  5. Skin Tests for Immediate Hypersensitivity
  6. Photopatch Testing
  7. Noninvasive Techniques for Quantification of Contact Dermatitis

Part VI: Allergic Contact Dermatitis Related to Specific Exposures

  1. Allergens from the Standard Series
  2. Cosmetics and Skin Care Products
  3. Allergens of Special Interest
  4. Metals
  5. Metalworking Fluids
  6. Plastic Materials
  7. Topical Drugs
  8. Dental Materials
  9. Clothing
  10. Shoes
  11. Occupational Contact Dermatitis
  12. Health Personnel
  13. Plants and Plant Products
  14. Pesticides
  15. Contact Allergy in Children
  16. Prevention and Therapy
  17. Legislation
  18. International Comparison of Legal Aspects of Worker Compensation for Occupational Contact Dermatitis
  19. Computers in the Management of Contact Dermatitis
  20. Contact Dermatitis Research Groups
  21. Patch Test Concentrations and Vehicles for Testing Contact Allergens
  22. Patch Testing with the Patients’ Own Products
  23. Dictionary of Contact Allergens: Chemical Structures, Sources and References


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Contact Dermatitis
Fourth edition
edited by P. J. Frosch

2006 • 1,136 pages • $289.00 + shipping
Texas residents please add 6.75 % sales tax

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