Diseases of the Breast summarizes the current knowledge of breast diseases, including their clinical features, management, underlying biologies, and epidemiologies.
In addition to complete coverage of malignant breast diseases, benign diseases are discussed in relation to subsequent breast cancer development.
Diseases of the Breast reviews all major clinical trials and summarizes the information they provide on early detection and management of breast cancer.
Close attention is also given to the increasing importance of molecular biology and genetics in this field. This edition features:
- more than thirty new contributors
- fourteen new or completely rewritten chapters
- more clinically oriented chapters
- a companion Website will offer the fully searchable text and an image bank
Contents
Breast Anatomy and Development
- Breast Anatomy and Development
- Molecular Mechanisms Regulating Breast Development
- Stem Cells in Breast Development and Carcinogenesis: Concepts and Clinical Perspectives
Diagnosis and Management of Benign Breast Diseases
- Physical Examination of the Breast
- Management of the Palpable Breast Mass
- Management of Disorders of the Ductal System and Infections
- Management of Breast Pain
- Abnormalities of the Breast in Pregnancy and Lactation
- Management of Gynecomastia
- Pathology of Benign Breast Disorders
Breast Imaging and Image-Guided Biopsy Techniques
- Screeing for Breast Cancer
- Imaging Analysis: Mammography
- Breast Ultrasound
- Imaging Analysis: Magnetic Resonance Imaging
- Imaging: New Techniques
- Image-Guided Biopsy of Nonpalpable Breast Lesions
- Management Summary on Breast Imaging
Epidemiology and Assessing and Managing Risk
- Inherited Genetic Factors and Breast Cancer
- Genetic Testin and Management of Patients with Hereditary Breast Cancer
- Nongenetic Factors in the Causation of Breast Cancer
- Management of Other High Risk Patients
- Chemoprevention: Clinical Aspects
In Situ Carcinoma
- Pathology and Biological Features of Premalignant Breast Disease
- Lobular Carcinoma In Situ: Biology and Pathology
- Lobular Carcinoma In Situ: Clinical Management
- Ductal Carcinoma In Situ and Microinvasive Carcinoma
Pathology and Biological Markers of Invasive Breast Cancer
- Breast Cancer Genomics
- Pathology of Invasive Breast Cancer
- Clincal Aspects of Estrogen and Progesterone Receptors
- ERBB2 Testing: Assessment of Status for Targeted Therapies
- Prognostic and Predictive Markers
- Gene Arrays, Prognosis, and Therapeutic Interventions
- Bone Marraw Micrometastases and Circulating Tumor Cells
Management of Primary Invasive Breast Cancer
- Evaluation of Patients with Metastasis Prior to Primary Therapy
- Staging of Breast Cancer
- Mastectomy
- Breast-Conserving Therapy: Conventional Whole Breast Irradiation
- Breast-Conserving Therapy: Accelerated Partial Breast Irradiation
- Breast Reconstruction
- Local Therapy for the Breast and Chest Wall
- Sentinel Lymph Node Dissection
- Axillary Dissection
- Axillary Irradiation
- Preserving and Restoring Function after Local Treatment
- Lymphedema
- Treatment of the Axilla and Other Regional Nodes
- Postmastectomy Radiation Therapy
- Adjuvant Systemic Therapy: Endocrine Therapy
- Adjuvant Systemic Therapy: Chemotherapy
- Adjuvant Systemic Therapy: Chemoendocrine
- Adjuvant Treatment of ERBB2 Positive Breast Cancer
- Adjuvant Systemic Therapy: Bisphosphonates
- Lifestyle Issues in Breast Cancer Survivors
- Management of Menopausal Symptoms in Breast Cancer Survivors
- Side Effects of Systemic Therapy: Neurocognitive, Cardiac, and Secondary Malignancies
- Pharmacologenomics of Systemic Therapy of Breast Cancer
- Guidelines for Adjuvant Systemic Therapy
Preoperative Systemic Therapy
- Preoperative Therapy for Operable Breast Cancer
- Preoperative Endocrine Therapy for Operable Breast Cancer
- Local-Regional Therapy Considerations in Patients Receiving Preoperative Chemotherapy
- Locally Advanced Breast Cancer
- Inflammatory Breast Cancer
- Management Summary on Preoperative Systemic Therapy
Special Therapeutic Problems
Chapters 64-69
Evaluation after Primary Therapy and Management of Recurrent Breast Cancer
Chapters 70-77
New Breast Cancer Therapeutic Approaches
Chapters 78-80
Site-Specific Therapy of Metastatic Breast Cancer
Chapters 81-90
Breast Cancer in Special Populations
Chapters 91-93
Issues in Breast Cancer Survivorship
Chapters 94-96
Other Considerations
Chapters 97-98
Index
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