This two-volume set provides a full account of the entire sequence of drug development, from conceptualizing the drug, creating a library of candidates, and conducting clinical trials, to optimizing the synthetic route, marketing the drug, and developing delivery methods.

Comprehensive in scope, the set bridges the gap between medicinal and process chemistry.

Discussion includes the discovery of agents for the treatment and management of bacterial infections, Parkinson's disease, psoriasis, ulcers and stomach pain, atopic dermatitis, asthma, and cancer.

Case studies examine the discovery of erythromycin analogs (antibiotics), Tagamet, and Ultiva (remifentanil).

Full chapters are devoted to combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics.

This work is available as a two-volume set at significant savings, see ordering details below or you can purchase the individual volumes as follows:

Volume 1: Drug Discovery thoroughly describes conceptualizing a drug, creating a library of candidates for testing, screening those candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and revising the drug as necessary.

Volume 2: Drug Development describes optimizing the synthetic route; manufacturing, outsourcing, and marketing the drug, including coloring; and developing delivery methods.

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