Chemical and Enzymatic Aspects
by Jack P. Uetrecht
Drug Metabolism is a comprehensive guide for recognizing the chemical underpinnings of drug metabolism.
Drug Metabolism provides extensive material to help understand drug metabolism within a biological context, and for predicting and mitigating adverse drug reactions.
Drug Metabolism:
- provides a review of kinetic aspects of drug metabolism
- presents detailed information describing oxidative enzymes and the oxidative pathways of drug metabolism
- discusses what makes a metabolite chemically reactive
Contents
- Background for Nonchemists
- Background for Chemists
- Oxidation Pathways and the Enzymes that Mediate Them
- Reductive Pathways
- Hydrolytic Pathways
- Conjugation Pathways
- Reactive Metabolites
Index