Drug Discovery for Nervous System Diseases
by Franz F. Hefti

Reflecting recent advances, Drug Discovery for Nervous System Diseases presents the latest techniques and approaches for drug discovery, organizing them according to diseases rather than classes of drugs or drug targets, as past books have done.

Written with optimistic anticipation of great progress still to come, this text provides both a guide to present realities and a look to future possibilities in this burgeoning field.

Coverage includes:

• Fundamentals of drug discovery
• Anxiety disorders
• Alzheimer's disease
• Parkinson's disease
• Ischemic stroke, brain, and spinal cord injury
• Sleep disorders
• Pain

This practical handbook features a uniform presentation for each chapter, with a brief description of existing drugs leading to recent molecular biological and genetic findings, translational research and the interface to clinical trials, and finally an outlook on future drug targets. Rich illustrations—schematic diagrams and tables—provide a dynamic visual experience throughout the text.

A unique and up-to-date guide to a field currently undergoing a major growth spurt, Drug Discovery for Nervous System Diseases offers both practitioners and advanced students an unparalleled resource.

Contents

1. Introduction.
2. Drug Receptors and the Fundamentals of Pharmacology.
3. Drug Discovery.
4. Drug Target Selection for Nervous System Diseases.
5. From Drug Target to Drug, Neuroscience Specific Problems.
6. Schizophrenia.
7. Depression.
8. Anxiety Disorders.
9. Alzheimer’s Disease.
10. Parkinson’s Disease.
11. Ischemic Stroke, Brain and Spinal Cord Injury.
12. Other Neurodegenerative Diseases.
13. Sleep Disorders.
14. Epilepsy.
15. Pain

Index

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