Field Flow Fractionation Handbook
edited by Martin Schimpf

Field Flow Fractionation (FFF) is an emerging separation technique, which has been proven successful in the analysis of pharmaceuticals, biotechnology products, polymers, soils, and foods, among others. This book contains a comprehensive description of the four primary FFF subtechniques, with specific examples and applications for each.

The Field-Flow Fractionation Handbook has many great values, one of which lies in the fact that the authors are experts in the respective subtechniques that they address, and so are able to advise the reader, from firsthand experience, on how to avoid certain pitfalls associated with developing and implementing FFF applications.

Contents

1. PRINCIPLES AND THEORY
   
   • The Field-Flow Fractionation Family: Underlying Principles
     
   • Retention--Normal Mode
     
   • Band Broadening and Plate Height
     
   • Resolution and Fractionating Power
     
   • Steric Field-Flow Fractionation and the Steric Transition
     
   • Optimization
     
   • Physicochemical Measurements and Distributions from Field-Flow Fractionation
     
   • Sedimentation FFF Methodology: Insights Through Computer Simulations
     
   • Programmed Field-Flow Fractionation: Retention
     
   • Programmed Field-Flow Fractionation: Fractionating Power and Optimization
   
   
2. TECHNIQUES AND INSTRUMENATIONS
   
   • Experimental Field-Flow Fractionation: Overview
     
   • Sample Preparation and Choice of Carrier Liquid in Field-Flow Fractionation
     
   • Experimental Field-Flow Fractionation: Practices and Precautions
     
   • Ancillary Equipment
     
   • Sedimentation Field-Flow Fractionation
     
   • Thermal Field-Flow Fractionation
     
   • Flow Field-Flow Fractionation
     
   • Asymmetrical Flow Field-Flow Fractionation
     
   • Electrical Field-Flow Fractionation
     
   • Other Field-Flow Fractionation Techniques
     
   • Sample Recovery
   
   
3. APPLICATIONS: INDUSTRIAL AND BIOMEDICAL
   
   • Latexes and Emulsions
     
   • Metal Particles
     
   • Miscellaneous Submicrometer-Sized Particles
     
   • Miscellaneous Particles ≥1 µm in Diameter
     
   • Lipophilic Polymers
     
   • Synthetic Polymers--Water Soluble
     
   • Protein Complexes and Lipoproteins
     
   • Cell Separations
   
   
4. APPLICATIONS: ENVIRONMENTAL
   
   • Overview of Environmental Applications
     
   • Characterization of Humic Substances
     
   • Aquatic Colloids
     
   • Investigation of Pollutant-Particle Association
     
   • Biological Particles of Environmental Interest

Appendices
Index

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