by Roland W. Herzog
Immunology of Gene Therapy is the first book of its kind to summarized and present a broad review of the latest immunological advances in the field of genetic therapy.
- Summarises and reviews the important field of genetic therapy with respect to the latest immunological advances in the lab and clinic
- Unique treatment of immunology and immunotherapy in gene - approached from a vector and target organ point of view rather than from the perspective a specific diseases
- Broad appeal - applicable for immunology and genetics / gene therapy, recombinant DNA studies, transplantation, virology, cancer research and tumor research
Immunology of Gene Therapy's unique organization, which approaches the topic from a vector and target organ point of view, rather than from a disease-specific perspective, reflects the ways in which gene therapies are being investigated today.
Contents
- The immunology of gene transfer: an overview
- Innate immune responses to nucleic acids
- The anti-viral Innate immune response
- Immune responses to adenoviral vectors
- Immune responses to lentiviral vectors
- Immune responses to adeno-associated virus vectors
- Immunology after in utero and neonatal gene transfer
- Immunology of hepatic gene transfer
- Immune responses to adenoviral, AAV, and lentiviral vector used for gene therapy of brain diseases
- Immunology of cutaneous gene transfer
- Immune responses to pulmonary gene therapy
- Induction of immune tolerance through gene transfer to hematopoietic stem cells
- Reconstitution of the immune system by gene therapy
- Genetics of the Immune Response to Proteins Expressed After Gene Transfer
- Immune modulation and transient suppression strategies
- Gene therapy for autoimmune diseases
- Engineering of viral capsids to evade the host immune system
Index
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