edited by John P Sundberg
Genetically Engineered Mice Handbook Summarizes commonly used and emerging technologies to bring beginners up to speed.
Features:
- Provides key URL's to access relevant public databases, with instructions in many languages
- Details specific microflora needed to optimize experimental results, while also listing those agents which can negatively impact experiments
- Examines new approaches used to generate repositories of embryonic stem cells that carry null mutations with reporter constructs
- Includes comprehensive information on basic issues of modern mouse biology and husbandry
- Contains a 12-page full-color insert to enhance detailed understanding
Contents
- Genetically Engineered Mice: Past, Present, and Future
- Sharing Reseach Tools: The Laboratory Mouse
- Managing Success: Mutant Mouse Repositories
- Mouse Genome Informatics: Database Access to Integrated Phenotype Data
- Genetic Resouce Databases in Japan
- Computational Pathology: Challenges in the Informatics of Phenotype Description in Mutant Mice
- Biological Methods for Archiving and Maintaining
- Mutant Laboratory Mice
- Mouse Genetic Resources without Germ Cells: Somatic Cell Nuclear Transfer and ES Technology
- The Present Status of Somatic Cell Cloning
- Exchangeable Gene Trapping
- Genetic Monitoring of Mice
- Microbiological Monitoring of Laboratory Mice
- Effect of Intestinal Flora on Phenotype
- Helicobacter pylori and Stomach Cancer
- Professional Use of Mutant Laboratory Mice in Research
- Phenotyping Postpartum Mutant Laboratory Mice and Determining Their Value for Human Diseaes
- Common Diseases Found in Inbred Strains of Laboratory Mice
- Colon Cancer and Polyposis Models: Makoto Mark Taketo
- Phenotypic Analysis of Mice with Steroid Deficiency
- External Genitalia Development: A Model System to Study Organogenesis
- Genetic Approaches to Investigate Retinoic Acid Functions in Mouse Development
- Mouse Models for Developmental Biology: Functional Analysis of Ror and Wnt Signaling
Index