Handbook of Basic Pharmacokinetics ... Including Clinical Applications, 7th edition remains a user-friendly consolidation of principles and techniques for practitioners, researchers, and students involved in the various applications of pharmacokinetics.

The book is current, accurate, and presented in a manner that fosters clinical application. Ten of the previous edition’s 39 chapters have been substantially updated.

Key Features:

• 39 chapters, 10 of which were substantially revised with new, relevant information and current reference citations
• More than 225 illustrations and tables
• Glossary
• Appendix comprises pharmacokinetic data on more than 790 drugs—more than 150 new to this edition—a highly useful resource for clinical practitioners

Contents

1. Definitions and Nomenclature
2. The LADMER System: Drug Liberation, Absorption, Distribution, Metabolism, Elimination, and Response
3. Organs, Tissues, Cells, and Organelles. Cell Membranes—Structure, Functions, and Properties
4. Drug Receptor Interactions
5. Absorption/Transport Mechanisms
6. Pka and Degree of Ionization
7. Lipid/Water Partition Coefficient
8. Physico-Chemical Factors Altering Biological Performance of Drugs
9. Biopharmaceutical Data of the Gastrointestinal Tract
10. Fluid Compartments and Circulatory System (Blood and Lymph)
11. Drug Biotransformation
12. Compartment Models
13. Determination of Rate Constants
14. Volume of Distribution and Distribution Coefficient
15. Excretion and Clearance of Drugs
16. Urinary and Biliary Recycling
17. Cumulative Urinary Excretion
18. Area Under the Blood Level-Time Curve
19. Pharmacokinetics of Single Dose Administration
20. Pharmacokinetics of Multiple Dosing
21. Compartment Model Independent Analysis
22. Pediatric Pharmacokinetics
23. Drug Dosage in Elderly Patients
24. Drug Dosage in Obese Patients
25. Drug Disposition in Pregnancy
26. Dosage Regimen Design
27. Drug Monitoring and Dose Adjustment
28. Physiological and Pathological Factors Influencing Drug Response
29. First Dose Size in Man. Forensic Pharmacokinetics
30. Nonlinear Pharmacokinetics
31. Curve Fitting
32. Correlation of Clinical Response with Drug Disposition
33. Bioavailability and Bioequivalence
34. Body Surface Area
35. Extracorporeal Methods of Drug Removal
36. Pharmacogenetics and Pharmacogenomics

Appendix
Index

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ORDER NOW Handbook of Basic Pharmacokinetics Including Clinical Applications Seventh edition by Wolfgang A. Ritschel 2009 • 490 pages • $66.00 + shipping Texas residents please add 6.75 % sales tax