Handbook of Endometrial Pathology provides a clinically pragmatic and diagnostically up-to-date basis for the pathological examination of the endometrium, one of the most commonly examined tissues in anatomical pathology.

Features:

• Concepts and details are presented in an accessible manner and controversial or unproven concepts are highlighted
• Emphasis on differential diagnosis in lesions that cause difficulty
• Covers histopathological concepts and details

Contents

Sampling the endometrium

• Sampling the endometrium
• Indications for sampling the endometrium
• When is the endometrial tissue sufficient?
• Tissue processing and artefacts

The normal endometrium

• General considerations
• Menstrual cycle
• Postmenopausal endometrium
• Dating the endometrium

Pregnancy

• Placentation
• Abortion
• Abnormal pregnancy
• Ectopic pregnancy
• Postpartum haemorrhage
• Pregnancy following therapy

Endometrial inflammation

• Normal endometrium
• Definition of endometritis
• Non-specific endometritis
• Morphological subtypes of endometritis

Functional disorders and dysfunctional bleeding

• Terminology
• Anovulatory cycles
• Luteal phase defect
• Irregular shedding of the endometrium
• Oestrogen deficiency
• Dysfunctional uterine bleeding

Iatrogenic disease

• Hormone Replacement Therapy
• Oral contraceptives
• Systemic progestogens
• Tamoxifen
• Gonadotrophin releasing hormone agonists
• Endometrial ablation
• Intrauterine contraceptive devices
• Other hormone treatment

Benign tumours and tumour-like conditions

• Papillary adenofibroma
• Endometrial stromal nodule
• Endometrial polyps
• Endometrial metaplasias

Endometrial hyperplasias

• Definition of endometrial hyperplasia
• Terminology of endometrial hyperplasias
• Natural history of endometrial hyperplasias
• Aetiology of endometrial hyperplasias
• Histopathological diagnosis of endometrial hyperplasias
• Other terminology

Malignant neoplasms

• Endometrial carcinoma
• Endometrial stromal sarcoma
• Mixed epithelial stromal tumours
• Miscellaneous tumours
• Secondary tumours

Gestational trophoblastic disease

• Hydatidiform mole
• Invasive mole
• Choriocarcinoma
• Placental site trophoblastic tumour
• Epithelioid trophoblastic tumour
• Exaggerated placental site reaction
• Placental site nodule or nodule

Index

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