Handbook of Bioseparations serves as an essential reference and guidebook for
separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories.
The commercial success of biotechnology products is highly dependent on the successful development and application of reliable and sensitive bioseparation methods. Handbook of Bioseparations primarily focuses on separations of proteins; however, separations of other materials of interest, such as nucleic acids and oligonucleotides, are also covered to assist in particular bioseparation problems.
Analytical Techniques Include:
- Chromatographic Methods
- Capillary Electrophoresis
- Isoelectric Focusing
- Mass Spectrometry
Separation and Purification Methods Include:
- Liquid-Liquid Distribution
- Displacement Chromatography
- Expanded Bed Adsorption
- Membrane Chromatography
- Simulated Moving Bed Chromatography
Contents:
- Bioseparations: An Overview
- Analysis of Protein Impurities in Pharmaceuticals Derived from Recombinant DNA
- Physicochemical Factors in Polypeptide and Protein Purification and Analysis by High-Performance Liquid Chromatographic Techniques: Current Status and Challenges for the Future
- Capillary Electrophoresis of Compounds of Biological Interest
- Isoelectric Focusing
- Mass Spectrometry of Bomolecules
- Liquid-Liquid Partitioning Methods for Bioseparations
- Separation of Nucleic Acids and Proteins
- Bioseparations by Displacement Chromatography
- Physicochemical Basis of Expanded-Bed Adsorption for Protein Purification
- Expanded-Bed Adsorption Process for Protein Capture
- Adsorptive Membranes for Bioseparations
- Simulated Moving-Bed Chromatography for Biomolecules
- Large-Scale Chromatographic Purification of Oligonucleotides
- Separation of Antibodies by Liquid Chromatography
- Processing Plants and Equipment
- Engineering Process Control of Bioseparation Processes
- Economics of Bioseparation Processes
- Future Developments
Index
to see books of related interest
