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Bioscience Reference from C.H.I.P.S.

Handbook of Bioseparations
Volume 2: Separation Science and Technology Series
Edited by Satinder Ahuja

Handbook of Bioseparations serves as an essential reference and guidebook for separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories.

The commercial success of biotechnology products is highly dependent on the successful development and application of reliable and sensitive bioseparation methods. Handbook of Bioseparations primarily focuses on separations of proteins; however, separations of other materials of interest, such as nucleic acids and oligonucleotides, are also covered to assist in particular bioseparation problems.

Analytical Techniques Include:

  • Chromatographic Methods
  • Capillary Electrophoresis
  • Isoelectric Focusing
  • Mass Spectrometry

Separation and Purification Methods Include:

  • Liquid-Liquid Distribution
  • Displacement Chromatography
  • Expanded Bed Adsorption
  • Membrane Chromatography
  • Simulated Moving Bed Chromatography

Contents:

  1. Bioseparations: An Overview

  2. Analysis of Protein Impurities in Pharmaceuticals Derived from Recombinant DNA

  3. Physicochemical Factors in Polypeptide and Protein Purification and Analysis by High-Performance Liquid Chromatographic Techniques: Current Status and Challenges for the Future

  4. Capillary Electrophoresis of Compounds of Biological Interest

  5. Isoelectric Focusing

  6. Mass Spectrometry of Bomolecules

  7. Liquid-Liquid Partitioning Methods for Bioseparations

  8. Separation of Nucleic Acids and Proteins

  9. Bioseparations by Displacement Chromatography

  10. Physicochemical Basis of Expanded-Bed Adsorption for Protein Purification

  11. Expanded-Bed Adsorption Process for Protein Capture

  12. Adsorptive Membranes for Bioseparations

  13. Simulated Moving-Bed Chromatography for Biomolecules

  14. Large-Scale Chromatographic Purification of Oligonucleotides

  15. Separation of Antibodies by Liquid Chromatography

  16. Processing Plants and Equipment

  17. Engineering Process Control of Bioseparation Processes

  18. Economics of Bioseparation Processes

  19. Future Developments

Index

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Handbook of Bioseparations
Volume 2: Separation Science and Technology Series
Edited by Satinder Ahuja
2000 722 pages $175.95 + shipping
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