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Handbook of RNA Biochemistry
2-Volume Set
Edited by Roland Karl Hartmann Albrecht Bindereif Astrid Schön and Eric Westhof
Handbook of RNA Biochemistry brings together numerous novel methods that were hitherto only available through the primary literature. The editors - themselves experienced RNA researchers - have gathered expert authors from the US and Europe for the ultimate in everyday working knowledge. To this end, all the techniques covered are treated with the user in mind, including detailed practical advice and an invaluable "troubleshooting" section.
The broad scope of the Handbook of RNA Biochemistry allows the side-by-side treatment of specialized methods with basic biochemical techniques for the isolation, characterization and functional analysis of RNA. All pertinent laboratory methods are presented in detail, including:
- RNA synthesis, modification and ligation
- Sequence and structure determination of RNA
- Isolation and purification of ribonucleoproteins
- RNA crystallization
- Single molecule studies on RNA
- Analysis of splice variants
- RNA imaging in vivo
- Modeling and prediction of RNA structure
- RNA microarrays
- Aptamer libraries and SELEX technology
- RNA interference
Handbook of RNA Biochemistry is a guide to successful experimentation for molecular biologists, biochemists and biotechnologists and of interest to every researcher experimenting with RNA.
Contents
Volume 1
- RNA Synthesis
- Enzymatic RNA Synthesis, Ligation, and Modification
- Chemical RNA Synthesis
- Structure Determination
- Molecular Biology Methods
- Biophysical Methods
- Fluorescence and Single Molecule Studies
Volume 2
- RNA Genomics and Bioinformatics
- Analysis of RNA Function
- RNA-Protein Interactions in vitro
- RNA-Protein Interactions in vivo
- SELEX
- RNAi
Appendix: UV Spectroscopy for the Quanitation of RNA
Index
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Handbook of RNA Biochemistry
2-Volume Set Edited by Roland Karl Hartmann, Albrecht Bindereif, Astrid Schön, and Eric Westhof
2005 • 931 pages • $469.00 + shipping
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