Medical book from C.H.I.P.S.

The Headaches
Third Edition
by Jes Olesen

The Headaches includes over 100 types of headaches and provides evidence-based treatment recommendations, including extensive tables of controlled clinical trials.


General Aspects of The Headaches

  • History of the Headache
  • Classification of Headache
  • Epidemiology of Headache
  • Impact of the Headache on the Individual and Family
  • Societal Burden of the Headache
  • The History and Examination of Headache Patients
  • Principles of Clinical Pharmacology, Randomized Controlled Clinical Trials, and Evidence-Based Medicine in Headache
  • Ethical Issues in Headache Research and Management

Basic Science Aspects of The Headaches

  • Anatomy of Muscles, Tendons, Joints, Blood Vessels, and Meninges
  • Anatomy and Physiology of Head Pain
  • Inhibition and Facilitation of Nociception
  • Peripheral and Central Sensitization Related to Headaches
  • Imaging Pain
  • Serotonin and Other Biogenic Amines
  • Nitric Oxide
  • Calcitonin Gene-Related Peptide and Other Peptides
  • Sex Hormones
  • Prostanoids and Other Inflammatory Mediators
  • Other Molecules Involved in Pain Transmission
  • Ion Channels Relevant to Pain
  • Triptan Signal Transduction
  • Animal Models of Headache
  • Human Models of the Headaches

The Migraines

  • The Migraines: Introduction
  • Epidemiology of Migraine
  • Migraine Comorbidity

Migraine Mechanisms

  • Genetics of Migraine
  • Spreading Depression
  • 5-Hydroxytryptamine Involvement in Migraines
  • Nitric Oxide Involvement in Migraines
  • CGRP Involvement in Migraines
  • Channelopathies and Their Possible Relation to Migraines
  • Neurogenic Inflammatory Mechanisms
  • Blood and Spinal Fluid in Migraines
  • Influence of Female Hormones on Migraines
  • Platelets and Immunology of Migraines
  • Hemodynamics and Neuroimaging of Migraines
  • Brain Metabolism in Migraines
  • Neurophysiology of Migraines
  • Autonomic Dysfunction in Migraines
  • Psychological Mechanisms of Migraines
  • Synthesis of Migraine Mechanisms

Migraine: Clinical Feaures

  • Symptomatology of Migraines without Aura
  • Migraines with Aura and Their Subforms
  • Diagnosis and Differential Diagnosis of Migraines
  • Prognosis of Migraines

Migraine: Management

  • General and Pharmacologic Approach to Migraine Management
  • Psychological and Behavioral Treatments of Migraines

Migraine: Acute Drug Treatment of The Attack

  • Nonsteroidal Anti-Inflammatory Drugs in the Acute Treatment of Migraines
  • Ergot Alkaloids in the Acute Treatment of Migraines
  • Triptans, 5-HT1B/1D Receptor Agonists in the Acute Treatmene of Migraines
  • Antiemetic, Prokinetic, Neuroleptic, and Miscellaneous Drugs in the Acute Treatment of Migraines
  • Prioritizing Acute Pharmacotherapy of Migraines

Migraine: Prophylactic Drug Management

  • -Adrenoceptor Blocking Drugs in Migraine Prophylaxis
  • Antiserotonin Drugs in Migraine Prophylaxis
  • Calcium Antagonists in Migraine Prophylaxis
  • Antiepileptic Drugs in Migraine Prophylaxis
  • Nonsteroidal Anti-Inflammatory and Miscellaneous Drugs in Migraine Prophylaxis
  • Prioritizing Prophylacitc Treatment of Migraines
  • Potential New Drugs for the Acute and Prophylatic Treatment of Migraines

Migraine: Special Types and Complications

  • Sporadic and Familial Hemiplegic Migraines
  • Basilar Migraines and Retinal Migraines
  • Status Migrainosus
  • Migrainous Infarction and Migraine Triggered Epilepsy
  • Chronic Migraines

Tension-Type Headaches, Cluster Headaches, and Other Primary Headaches

  • Tension-Type Headache: Introduction
  • Epidemiology of Tension-Type Headaches

Tension-Type Headache: Pathophysiology

  • Genetics of Tension-Type Headaches
  • Human Studies of Experimental Pain From Muscle
  • Sensitization of Myofascial Pain Pathways in Tension-Type Headaches
  • Neurophysiology of Tension-Type Headaches
  • Hemodynamics and Muscle Metabolism of Tension-Type Headaches
  • Temporomandibular Disorders and Tension-Type Headaches
  • Psychological Mechanisms of Tension-Type Headaches
  • Biochemistry of Blood and Cerebrospinal Fluid in Tension-Type Headaches
  • Synthesis of Tension-Type Headache Mechanisms

Tension-Type Headache: Clinical Features

  • Symptomatology of Episodic Tension-Type Headaches
  • Symptomatology of Chronic Tension-Type Headaches
  • Differential Diagnosis and Prognosis of Tension-Type Headaches

Tension-Type Headache: Management

  • General Approach to Treatment of Tension-Type Headaches
  • Psychological Treatments of Tension-Type Headaches
  • Physiotherapy of Tension-Type Headaches
  • Acute Pharmacotherapy of Tension-Type Headaches
  • Prophylactic Pharmacotherapy of Tension-Type Headache

Cluster Headache

  • Cluster Headaches: Introduction and Epidemiology
  • Genetics of Cluster Headaches
  • Anatomy and Pathology of Cluster Headaches
  • Biochemistry, Circannual and Circadian Rhythms, Endocrinology, and Immunology of Cluster Headaches
  • Neurophysiology and Autonomic Dysfunction in Cluster Headaches
  • Neuroimaging in Trigeminal Autonomic Cephalgias
  • Synthesis of Cluster Headache Pathophysiology
  • Symptomatology of Cluster Headaches
  • Diagnosis, Differential Diagnosis, and Prognosis of Cluster Headaches
  • General Approach to the Management of Cluster Headaches
  • Acute Treatment of Cluster Headaches
  • Preventive and Surgical Management of Cluster Headaches
  • Paroxysmal Hemicrania
  • Sudden Unilateral Neuralgiform Pain with Conjunctival Injection and Tearing

Other Primary Headaches

  • Primary Stabbing, Cough, Exertional, and Thunderclap Headaches
  • Primary Headache Attributed to Sexual Activity
  • Hypnic Headaches
  • Hemicrania Continua
  • New Daily Persistent Headache

The Secondary Headaches

  • Acute Posttraumatic Headaches
  • Chronic Posttraumatic Headaches
  • Headache Attributed to Whiplash Injury

Headache Attributed to Vascular Disorder

  • Ischemic Stroke and Spontaneous Intracerebral Hematoma
  • Unruptured Vascular Malformation and Subarachnoid Hemorrhage
  • Arteritis
  • Carotid or Vertebral Artery Pain
  • Cerebral Venous Thrombosis

Headache Attributed to Nonvascular Intracranial Disorder

  • High Cerebrospinal Fluid Pressure
  • Low Cerebrospinal Fluid Pressure
  • Pseudomigraine with Pleocytosis
  • Intracranial Neoplasms

Headache Attributed to a Substance, an Infection, or a Disorder of Homeostasis

  • Headache Associated with Acute Substance Use or Exposure
  • Medication Overuse Headaches
  • Headache Attributed to Infection
  • Headache Attributed to a Disorder of Homeostasis

Headache or Facial Pain Attributed to a Cranial, Cervical, or Psychiatric Disorder

  • Disorder of the Skull and Cervical Spine
  • Ocular Disorder
  • Disorder of Ear, Nose, and Sinus
  • Headache Attributed to Orofacial/Temporomandibular Pathology
  • Headache Attributed to Psychiatric Disorder

Cranial Neuralgias, Nerve Trunk Pain, and Deafferentation Pain

    Pain of Cranial Nerve and Cervical Nerve Origin Other Than Primary Neuralgias

  • Trigeminal Neuralgia and Other Facial Neuralgias
  • Central Pain in the Face and Head

Headaches in Children, and Adolescents

  • History and Examination of Infants, Children, and Adolescents with Headaches
  • Childhood Migraine and Related Syndromes
  • Tension-Type Headaches and Other Nonmigraine Primary Headaches in the Pediatric Population
  • Secondary Headaches in the Pediatric Population

Special Problems in the Headaches and Their Management

  • Headache During Pregnancy and Lactation
  • Headaches and Sleep
  • Headaches in the Elderly
  • Headache in Patients with Coexisting Other Pain Disorder
  • Headaches in Patients with Coexisting Psychiatric Disease
  • Headaches in Patients with Coexisting Medical Disease
  • Headaches in the Emergency Room


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The Headaches
Third Edition
by Jes Olesen

2006 1169 pages $234.00 + shipping
Texas residents please add 6.75 % sales tax

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