Intended for those requiring an expert source of guidance for the quick detection and control of HIT, Heparin-Induced Thrombocytopenia, 4th editiion:

• contains new chapters on novel pharmacotherapies, recent drug approvals, current dosing guidelines, and the advantages and limitations of alternative anticoagulants
• reviews the immune basis and pathogenesis, clinical features, differential diagnosis,and laboratory testing for HIT antibodies, and provides evidence-based guidelines for the recognition, treatment, and prevention of this disorder
• details actions that should and should not be taken after the identification of HIT
• helps physicians select from a variety of new treatment options, and determine which of these agents are safe and effective for their patients
• provides a comprehensive overview of clinical and laboratory studies on HIT

This Fourth Edition reinforces its standing as the leading guide to the accurate diagnosis and management of HIT by identifying key signs and symptoms of this disorder and providing clear intervention strategies, including detailed information on treatment paradoxes and the use of alternative anticoagulants to manage these critical circumstances.

Contents

1. History
2. Clinical
3. Frequency
4. Hep-Plt
5. Antigens
6. Molecular Immunopathogenesis
7. Sulfated Polysaccharides
8. Fc Receptor
9. Endothelium
10. Laboratory Testing for HIT Antibodies
11. Pseudo-HIT
12. Treatment Overview
13. Danaparoid
14. Lepirudin
15. Argatroban
16. Bivalirud
17. Fondaparinux
18. Hemodialysis
19. Cardiac Surgery
20. Pediatric HIT
21. Myths & para-doxes of HIT

Index

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