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Hypoxia and Exercise
by Robert Roach

Hypoxia and Exercise focuses on cutting edge research at the interface of hypoxia and exercise and covers the range from molecular mechanisms of muscle fatigue and muscle wasting to whole body exercise on the world's highest mountains.


Hypoxia Honoree

  • A Tribute to John Burnard West
  • Adventures in High-Altitude Physiology

Exercise-Induced Hypoxemia (EIH): Causes and Consequences

  • Exercise Induced Arterial Hypoxemia: The Role of Ventilation-Perfusion Inequality and Pulmonary Diffusion Limitation
  • Intrapulmonary Shunt During Normoxic and Hypoxic Exercise in Healthy Humans
  • Exercise-Induced Arterial Hypoxemia: Consequences for Locomotor Muscle Fatigue

Causes and Effects of Sleep-Disordered Breathing

  • Mechanisms of Sleep Apnea at Altitude
  • Control of Cerebral Blood Flow During Sleep and the Effects of Hypoxia
  • Neural Consequences of Sleep Disordered Breathing: The Role of Intermittent Hypoxia

Genetics, Genomics and Adaptation to High Altitude

  • Finding the Genes Underlying Adaptation to Hypoxia Using Genomic Scans for Genetic Adaptation and Admixture Mapping
  • An Evolutionary Model for Identifying Genetic Adaptation to High Altitude
  • Hypoxic Preconditioning and Erythropoietin Protect Retinal Neurons from Degeneration

Blocking Stress Pathways with Cell-Permeable Membranes

  • Blocking Stress Signaling Pathways with Cell Permeable Peptides
  • Jnk Pathway as Therapeutic Target to Prevent Degeneration in the Central Nervous System
  • Salvage of Ischemic Myocardium: A Focus on Jnk

The Impact of Immobilization and Hypoxia on Skeletal Muscle

  • Mitochondrial Reactive Oxygen Species are Required for Hypoxic Hifα Stabilization
  • Hypoxia-Induced Gene Avtivity in Disused Oxidative Muscle

Hypoxic Vasoregulation: Interactions of Red Cells, Endothelium and Smooth Muscle

  • Role of the Red Blood Cells in Nitric Oxide Homeostasis and Hypoxic Vasodilation
  • Expression of the Heterotrimeric G Protein Gi and Atp Release are Impaired in Erythrocytes of Humans with Diabetes Mellitus
  • Red Blood Cells and Hemoglobin in Hypoxic Pulmonary Vasoconstriction

Hypoxia: State of the Art

  • Dose-Response of Altitude Training: How Much Altitude is Enough?
  • The Eye at Altitude
  • Lake Louise Consensus Methods for Measuring the Hypoxic Ventilatory Response

Future Directions in Hypoxia Research

  • Pulmonary Hypertension in High-Altitude Dwellers: Novel Mechanisms, Unsuspected Predisposing Factors
  • Gene Hunting in Hypoxia and Exercise


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Hypoxia and Exercise
by Robert Roach
2006 • 353 pages • $225.00 + shipping
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