From Target Selection Through Lead Optimization
edited by Jeffrey S. Handen
Industrialization of Drug Discovery delineates the basic tenets underlying modern drug discovery, how they have evolved, and their use in various approaches and strategies.
Features:
- Provides a critical review of underused industrial technology available to the pharmaceutical industry
- Discusses financial, regulatory, and ethical issues associated with drug discovery and suggests possible solutions
- Explores possible pathways to more specific targets, more selective compounds, and less development time
- Focuses on how modern industrial approaches can be applied to significantly impact the productivity gap
- Offers insight into the underlying principles that guide the FDA's actions
- Addresses financial and investment concerns related to discovering new therapies for unmet medical needs
- Examines the international scope of drug development, considering virtual and global collaboration
Contents
- Drug Discovery in the Modern Age: How We Got Here and Where Do We Go
- The Regulatory Age
- Industrialization Not Automation
- Compound Management
- High-Throughput Screening
- Parallel Lead Optimization
- Knowledge Management
- Understanding the Value of Research
- Collaboration in a Virtual and Global Environment
- From Genome to Drug: Ethical Issues
Index
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