Intraocular Drug Delivery studies the most recent advances in the development of ocular drug delivery systems.

Features:

• Covers current methods, clinical applications, and new delivery systems to treat and prevent proliferative eye disease
• Examines the factors that trigger and perpetuate intraocular wound healing in diseases such as proliferative vitreoretinopathy
• Reviews the results of clinical trials of new sustained delivery implants
• Analyzes the potential of intraocular drug delivery for the treatment of posterior segment diseases

Contents

General

• Retinal Drug Delivery
• Blood Retinal Barrier
• Neuroprotection
• Regulatory Issues in Drug Delivery to the Eye

Specific Delivery Systems

• Intravitreal Injection
• Anti-angiogenic Agents
• Intravitreal Antimicrobials
• Pharmacologic Retinal Reattachment with INS37217 (Denufosol Tetrasodium), a Nucleotide P2Y2 Receptor Agonist
• Cell Based Delivery Systems
• Photodynamic Therapy
• Thermal Sensitive Liposomes
• Gene Therapy for Retinal Disease
• Biodegradable Systems
• Transscleral Drug Delivery to the Retina and Choroid
• Nondegradable Intraocular Sustained Release Drug Delivery Devices

Local Drug Delivery Approach to Specific Clinical Diseases

• Age-Related Macular Degeneration
• Photodynamic Therapy Human Clinical Studies
• Age-Related Macular Degeneration Drug Delivery
• Intraocular Sustained Drug Delivery in Uveitis
• Drug Delivery for Proliferative Vitreoretinopathy: Prevention and Treatment
• Pharmacological Treatment in Diabetic Macular Edema
• Retinal Vein Occlusion
• Cytomegalovirus (CMV) Retinitis
• Endophthalmitis

Index

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