Kindling 6 provides valuable summaries of the ongoing research on seizure development, with an emphasis on mechanisms, consequences, and potential treatments that might offset epileptogenesis.

Contents

Pathogenesis of Kindling

• Developmental Temporal Lobe Epilepsy in Amygdala Kindled Kittens: An Update
• Prenatal Betamethasone Exposure Suppresses Kindling Epileptogenesis in Immature Rats
• Development of Kindling in Immature Fast and Slow Kindling Rats
• Neonatal Heat-Induced Convulsions Affect Behaviours in Neonatal, Juvenile and Adult Rats
• Experimental Absence Versus Amygdaloid Kindling
• Pentylenetetrazol-Induced Kindling as a Model of Absence and Convulsive Forms of Epilepsy

Electrophysiology

• Sodium Current Properties in Different Models of Epilepsy
• Kindling the Gabaergic Phenotype of the Glutamatergic Granule Cells
• Hippocampal Kindling and GABA_B Receptor Functions
• Altered Interaction Between the Entorhinal Cortex and Hippocampus in Amygdala Kindled Rats

Anatomy, Morphology, and Neural Circuitry

• Nature and Consequences of Seizures Originating in the Brainstem
• Involvement in the Claustrum and Ventromedial Thalamus in Epileptogenesis
• From Ultrastructure to Networks: Kindling-Induced Changes in Neocortex
• Kindling as a Tool for Studying the Role of Subcortical Structures in Limbic Seizures
• Kindling, Epilepsy, and the Plasticity of Network Synchronization

Genes, Species, and Strains

• Electrophysiological and Anatomical Differences, Behavioral Comorbidities and Gene Expression in Fast and Slow Kindling Rat Strains
• Gene Expression Changes in Kindling
• A Proteomic Approach to the Molecular Analysis of Kindling

Synaptic Pharmacology and Neurochemistry

• Amygdala Metabotropic Glutamate Receptors and Kindling
• Induction of B₁ Bradykinin Receptors in the Kindled Brain
• Galanin and Kindling
• Kindling, Neurotrophins and Axon-Guidance Factors
• Conditional Deletion of TRKB Prevents Epileptogenesis in the Kindling Model
• Neuropeptide Y and its Receptors in Kindling Epileptogenesis

Behavioral Consequences of Kindling

• Contribution of Pre Kindling Affective State to Hemispheric Differences in the Effects on Anxiety of Basolateral Amygdala Kindling
• Effects of Kindling on Spatial Memory: Characteristics and Mechanisms
• A Potential Role for the Hippocampus in the Expression of Kindling-Induced Fear
• Does Inadvertent Conditioning Contribute to the Major Features of Kindling?

Drugs and Interventions Against Kindling

• Contingent Tolerance and Cross Tolerance to Anticonvulsant Effects in Amygdala-Kindled Seizures: Mechanistic and Clinical Implications
• Mechanisms of Pharmacoresistance in the Phenytoin-Resistant Kindled Wistar Rat
• Development of New Anticonvulsants Using the Kindling Model
• Cannabinoids and Kindling
• Low Frequency Sine Wave Stimulation Decreases the Incidence of Kindled Seizures

Clinical Relevence of Kindling for our Understanding of Epilepsy in Patients

• Predisposed Susceptibility in Primate Epileptogenesis and Anti-Epileptogenesis
• Natural History of Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis: How Does Kindling Compare with Other Commonly Used Animal Models
• Clinical Evidence of Epilepsy-Related Plasticity
• Pathological Sensitization of the Dopamine System in Experimental Epileptogenesis: Implication for the Mechanism of Epileptic Psychosis

Index

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ORDER NOW Kindling 6 by Michael E. Corcoran 2005 • 415 pages • $174.00 + shipping Texas residents please add 6.75% sales tax