Medical Book from C.H.I.P.S.

Lung and Heart-Lung Transplantation
edited by Joseph P. Lynch

Lung and Heart-Lung Transplantation focuses on cumulative data from the International Registry with data on outcomes associated with LT and HLT worldwide.


  • Contains chapters on immune tolerance, regulatory T cells, dendritic cells, and animal models for a clear framework to understand the pitfalls inherent in clinical LT
  • Considers immunologic issues associated with lung transplantation such as acute and chronic allograft rejection
  • Discusses specific parameters and physiologic, radiographic, and clinical criteria for various disease states that influence practitioners to refer patients for lung transplantation
  • Details the impact of panresistant Pseudomonas aeruginosa, Burkoholderia cepacea, aspergillus, and atypical mycobacteria on morbidity and mortality
  • Provides a global perspective on the current and future role of LT


Clinical Aspects

  • Historical Overview of Lung and Heart-Lung Transplantation

Immunology of Transplantation: Basic Science

  • Basic Immunologic Concepts Involved in Lung Transplantation
  • Allogeneic Recognition
  • Tolerance
  • Immunological Techniques for Assessing Alloreactivity in Potential Organ Recipients

Clincal Aspects

  • COPD and ?1-Antitrypsin Deficiency Emphysema
  • Cystic Fibrosis and Bronchiectasis
  • Pulmonary Hypertension
  • Lung Transplantation for Interstitial and Cystic Lung Diseases
  • Pediatric Lung Transplantation
  • Living Lobar Lung Transplantation
  • Controversies in Transplantation
  • Hear-Lung Transplantation

Organ Allocation and Donor Availability

  • Allocation of Donor Organs
  • European Experience
  • Australian Experience
  • Lung Preservation Techniques
  • Operative Techniques Utilized in Lung Transplantation

Immunosuppresion: Action, Efficacy, Drug Interactions and Toxicities

  • Cyclosporine, Tacrolimus, Sirolimus, Azathioprine, Mycophenolar, Mofetil, Corticosteroids
  • Lympholytic Agents
  • Novel and Future Approaches to Immunosuppression

Complications in Lung Transplantation

  • Early Graft Dysfunction and Primary Graft Failure Following Lung Transplantation: Clinical Features, Recognition, and Treatment
  • Early Graft Dysfunction Following Lung Transplantation: Pathogenesis and Impact of Late Allograft Function
  • Airway Complications

Infectious Complications

  • Viral Infections Complication Lung and Solid Organ Transplantation
  • Invasive Fungal Infections Complicating Lung and Solid Organ Transplantation
  • Bacterial Infections

Lung Allograft Rejection

  • Clinical Features of Acute Rejection: Incidence, Clinical Features, Management
  • Histology of Lung or Heart-Lung Allograft Rejection
  • Animal Models of Acute and Chronic Rejection

Chronic Allograft Rejection

  • Obliterative Bronchiolitis: Incidence, Clinical Features, Histology, Diagnosis, and Treatment
  • Pathogenesis of Bronchiolitis Obliterans Syndrome
  • Pulmonary Physiology Post-Transplant
  • Role of Surveillance Bronchoscopy
  • Thoracic Imaging Post Lung Transplant

Long-Term Complications of Lung Transplantation

  • Cardiac, Renal, Hypertension, Lipids, Metabolic, Osteoporosis
  • Neoplasia Following Transplantation


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Lung and Heart-Lung Transplantation
edited by Joseph P. Lynch
2006 992 pages $248.95 + shipping
Texas residents please add 6.75 % sales tax

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