There has been a growing interest in exploring the role of lycopene in the prevention of a variety of nutritional and health issues in humans, including some cancers and cardiovascular diseases.

Recently, many case studies using cell cultures, animal models, and epidemiological investigations have shown a relationship between lycopene intake and a lowered risk of contracting some cancers and various chronic diseases.

Increasingly, clinical evidence supports the role of lycopene as a nutrient with important health benefits, since it appears to provide protection against a broad range of epithelial cancers.

The possibility that consumption of lycopene-rich foods may reduce the risk of such diseases has prompted numerous in-depth studies of the levels of lycopene in foods and of correlations between dietary lycopene and certain diseases.

Lycopene will serve as a reference for providing a better understanding of the role of lycopene in promoting health, and by encouraging a deeper understanding of approaches to a healthy diet and life.

Contents

Part 1: Characterization of Lycopene from Chemistry to Basic Physiological Functions

• Lycopene Overview: What it is and What it Does
• Stability of Lycopene During Food Processing and Storage
• Lycopene Metabolites: Apo-lycopenals
• Non-covalent Binding of Lycopene and Lycophyll
• Risk Assessment of Lycopene

Part 2: Biochemical and Physiological Features of Lycopene's Effects

• Lycopene and Peroxynitrite Modifications
• Lycopene and Down-regulation of Cyclin D1, pAKT and pBad
• Lycopene and Chylomicrons
• Lycopene and Chromosomal Aberrations
• Lycopene and Lycopene-enriched Prostasomes
• Topically Applied Lycopene and Antioxidant Capacity
• Lycopene and Cardiovascular Diseases
• Effects of Lycopene and Monounsaturated Fat Combination on Serum Lycopene, Lipid and Lipoprotein Concentrations
• Lycopene: Cataract and Oxidative Stress
• Lycopene and Bone Tissue

Part 3: Lycopene and Cancer

• Lycopene and Its Potential Role in Prostate Cancer Prevention
• Lycopene and Urokinase Receptor Expression in Prostate Cancer Cells
• Lycopene and Lung Cancer
• Breast Cancer and Lycopene
• Lycopene and Colon Cancer

Index

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