Now in its Fourth edition, this comprehensive, practical, and thoroughly illustrated reference offers valuable guidance in the diagnostic interpretation of lymph node biopsies. It provides encyclopedic coverage of all the various nonmalignant lesions, lymphomas, other neoplasms, and metastatic tumors in lymph nodes. The discussion of each pathologic entity includes definition, clinical syndrome, histopathology, and differential diagnosis.

This edition has more than 700 illustrations, including over 600 in full color. Dr. Ioachim is joined by a new co-editor, L. Jeffrey Medeiros, MD, from the University of Texas MD Anderson Cancer Center. All chapters have been extensively revised and a new chapter on genetics has been added.

Contents

Part One: The Normal Lymph Node

1. The Normal Lymph Node

Part Two: Diagnostic Methods

2. The Lymph Node Biopsy
3. Cytopathology
4. Electron Microscopy
5. Cytochemistry
6. Immunohistochemistry
7. Flow Cytometry
8. Molecular Diagnosis

Part Three: Lymphadenitides

9. Infectious Mononucleosis Lymphadenitis
10. Cytomegalovirus Lymphadenitis
11. Herpes Simplex Virus Lymphadenitis
12. Varicella-Herpes Zoster Lymphadenitis
13. Vaccinia Lymphadenitis
14. Measles Lymphadenitis
15. Human Immunodeficiency Virus Lymphadenitis
16. Ordinary Bacterial Lymphadenitis
17. Cat-Scratch Lymphadenitis
18. Bacillary Angiomatosis of Lymph Nodes
19. Lymphogranuloma Venercum Lymphadenitis
20. Syphilitic Lymphadenitis
21. Lymphadenitis of Whipple Disease
22. Mycobacterium tuberculosis Lymphadenitis
23. Nontuberculous Mycobacterial Lymphadenitis
24. Mycobacterium Leprae Lymphadenitis
25. Cryptococcus Lymphadenitis
26. Histoplasma Lymphadenitis
27. Coccidioidomycosis Lymphadenitis
28. Pneumocystis Lymphadenitis
29. Toxoplasma Lymphadenitis
30. Leishmania Lymphadenitis
31. Filaria Lymphadenitis

Part Four: Lymphadenopathies

32. Reactive Lymphoid Hyperplasia
33. Atypical Lymphoid Hyperplasia
34. Progressive Transformation of Germinal Centers
35. Kimura Lymphadenopathy
36. Sinus Histiocytosis with Massive Lymphadenopathy
37. Kikuchi Lymphadenopathy
38. Sarcoidosis Lymphadenopathy
39. Systemic Lupus Lymphadenopathy
40. Rheumatoid Lymphadenopathy
41. Dermatopathic Lymphadenopathy
42. Castleman Lymphadenopathy
43. Lymphadenopathies of Salivary Glands
44. Tumor-Reactive Lymphadenopathy
45. Drug-Induced Lymphadenopathy: Methotrexate
46. Drug-Induced Lymphadenopathy
47. Lymph Node Infarction
48. Vascular Transformation of Sinuses
49. Proteinaceous Lymphadenopathy
50. Lipid Lymphadenopathy
51. Silicone Lymphadenopathy
52. Lymphadenopathy of Metal Debris Associated with Joint Prostheses
53. Gold Lymphadenopathy
54. Epithelial Cell Inclusions in Lymph Nodes
55. Nevus Cell Inclusions in Lymph Nodes

Part Five: Lymphomas

56. Nomenclature and Classfication of Lymphomas
57. Hodgkin Lymphoma: Classical
58. Hodgkin Lymphoma: Nodular Lymphocyte Predominant
59. Lymphoblastic Leukemia/Lymphoma
60. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
61. Lymphoplasmacytic Lymphoma
62. Hairy Cell Leukemia
63. Nodal Marginal Zone B-Cell Lymphoma
64. Follicular Lymphoma
65. Diffuse Follicular Center Cell Lymphoma
66. Mantle Cell Lymphoma
67. Diffuse Large B-Cell Lymphoma
68. Mediastinal Large B-Cell Lymphoma
69. Burkitt Lymphoma
70. Lymphomas of Salivary Glands—Composite Lymphoma
71. Adult T-Cell Leukemia/Lymphoma
72. Mycosis Fungoides
73. Peripheral T-Cell Lymphoma, Unspecified
74. Angioimmunoblastic T-Cell Lymphoma
75. Anaplastic Large-Cell Lymphoma

Part Six: Granulocytic, Histocytic, and Dendridic Cell Neoplasms

76. Myeloid Sarcoma
77. Histiocytic Sarcoma
78. Dendritic Cell Neoplasms

Part Seven: Lymphoproliferative Disorders Associated with Immune Deficiency

79. Lymphoproliferative Disorders Associated with Congenital Immune Deficiencies
80. Post-Transplant Lymphoproliferative Disorders
81. Lymphomas Associated with Acquired Immunodeficiency Syndrome (AIDS)

Part Eight: Spindle Cell Neoplasms of Lymphnodes

82. Palisaded Myofibroblastoma
83. Inflammatory Pseudotumor of Lymph Nodes

Part Nine: Vascular Neoplasms of Lymphnodes

84. Hemangiomas/Hemangioendotheliomas
85. Kaposi Sarcoma

Part Ten: Meta Static tumors in Lymphomas

86. Tumor Metastases in Lymph Nodes
87. Metastatic Melanoma
88. Metastatic Breast Carcinoma
89. Metastatic Nasopharyngeal Carcinoma
90. Metastatic Papillary thyroid Carcinoma
91. Metastatic Renal Cell Carcinoma
92. Metastatic Seminoma
93. Metastatic Prostatic Carcinoma
94. Metastatic Mucinous Adenocarcinoma
95. Metastatic Neuroendocrine Tumors
96. Metastatic Neruoblastoma
97. Metastatic Ewing Sarcoma/Peripheral Neuroectodermal Tumor
98. Metastatic Rhabdomyosarcoma

Index

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