Methods for Structural Analysis of Protein Pharmaceuticals details the nature of the different analytical techniques and how they are relevant for characterizing pharmaceutical proteins.

In addition to serving the analytical chemist, this book is needed by the formulation scientist who is responsible for design and formulation of a pharmaceutical protein that can be monitored during production and over time. It also will be useful for professionals in the pharmaceutical/biotechnology industry on basic aspects of proteins.

Contents

1. Ultraviolet Absorption Spectroscopy
2. Pluorescence Spectroscopy
3. Circular Dichroism Spectroscopy
4. Fourier Transform Infrared Spectroscopy
5. Raman Spectroscopy
6. Nuclear Magnetic Resonance Spectroscopy
7. Light Scattering
8. Liquid Chromatography
9. Capillary Electrophoresis
10. Analytical Ultracentrifugation
11. Field-Flow Fractionation
12. Mass Spectrometery: Protein Conformational Analysus and Molecular Recognition
13. Mass Spectrometry: Proteomics
14. Immunoassays
15. Surface Plasmon Resonance
16. Microarray-Based Methods
17. Calorimetry
18. Atomic Force Microscopy
19. Molecular Modeling
20. Concluding Remarks: Analytical Methods of Protein Formulations

Index

Methods for Structural Analysis of Protein Pharmaceuticals is Volume 3 in the series: Biotechnology: Pharmaceutical Aspects. Other volumes in this series include:
Volume 1: Pharmaceutical Profiling in Drug Discovery for Lead Selection
Volume 2: Lyophilization for Biopharmaceuticals

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