Mitochondria in Health and Disease describes effects of drugs, nutrients, and hormones on mitochondrial function.

Features:

• Written by experts in their respective fields of mitochondrial study
• Includes bioenergetics of mitochondria, population surveys using mitochondria, oxidative stress and alterations of gene expression in human aging, and mitochondrial mutations in vision
• Provides an overview of mitochondria as well as specific functions and effects of mutation
• Relates mitochondrial function to disease

Contents

• Introduction to Mitochondria
• Bioenergetics of Mitochondria
• Mitochondrial Genome and Mitochondrial Function
• Mitochondrial Diseases in Growth and Development
• Using Mitochondria in Population Surveys
• Mitochondrial DNA Mutation, Oxidative Stress and Alterations of Gene Expression in Human Aging
• Mitochondrial Mutations in Vision
• Mitochondrial DNA in Cardiomyopathies
• Mitochondria in Diabetes
• Drugs, Nutrients and Hormones in Mitochondrial Function
• Bacterial F1F0ATP Synthase as a Model for Complex V
• Cybrids and the Manipulation of Mitochondrial Genotype
• Animal Modelling: From Transgenics to Transmitochondrial Models
• BHE/Cdb Rats as Tools to Study Mitochondrial Mutation

Index

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