Molecular Pathology in Clinical Practice is the current standard in molecular testing for practicing pathologists, and residents and fellows in training>

This book is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management.

Discussion of each diagnostic test includes its:

• clinical significance
• available assays
• quality control and lab issues
• interpretation
• reasons for testing

Coverage extends to HIV, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage, and much more.

Molecular Pathology in Clinical Practice includes 189 illustrations, 45 in full-color.

Partial Contents

1. Basics of molecular pathology
2. Molecular pathology methodologies

Section I: Genetics

3. Genetic counseling
4. Pedigree analysis and risk assessment
5. Bayesian analysis
6. Developmental disabilities
7. Neuromuscular diseases
8. Molecular genetic testing for metabolic disorders
9. Fibroblast growth factor receptor-related skeletal disorders
10. Cystic fibrosis
11. Deafness
12. Coagulation disorders
13. Hematologic disorders
14. Cardiovascular disease
15. Neurodegenerative disorders
16. Skin and connective tissue disorders

Section II: Inherited Cancers

17. Inherited breast cancer
18. Familial adenomatous polyposis and Turcot and Peutz-Jeghers syndromes
19. Hereditary nonpolyposis colorectal cancer
20. Multiple endocrine neoplasia syndromes
21. The neurofibromatoses
22. TP53 mutation and Li-Fraumeni syndromw
23. Von Hippel-Lindau disease

Section III: Solid Tumors
chapters 24-29

Section IV: Neoplastic Hematopathology
chapters 30-35

Section V: Infectious Diseases
chapters 36-43

Section VI: Identity Testing
chapters 44-47

Section VII: HLA Typing

48. Molecular HLA typing

Section VIII: Laboratory Management Issues

49. Molecular pathology laboratory management
50. From research to clinical practice

Index

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