• Contributions from leading practioners in the field
• Includes all the latest developments with an insight into future approaches.
• Discussion on a combination of techniques and concepts

Molecular Analysis and Genome Discovery is a comprehensive overview of recent developments in the fast moving field of molecular based diagnostics of disease markers. Key concepts and applications are provided alongside practical information on current techniques currently being researched and developed.

Each chapter offers an up-to-date analysis of the subject encompassing the very latest technology platforms. An indispensable resource for all students taking courses in molecular medicine, biotechnology and molecular biology and also a useful reference for researchers in the biotechnology and pharmaceutical industries.

Contents

1. Pharmacogenetics and Pharmacogenomics: An Overview
2. Quantitative TaqMan Real-time PCR: Diagnostic and Scientific Applications
3. Hybridization Probes for Real-time PCR
4. An Overview of Genotyping and Single Nucleotide Polymorphisms (SNP)
5. High-throughput Mutation Screening
6. Determination of Nucleic Acid Sequences by Pyrosequencing
7. An Introduction to DNA Chips
8. Overview of Microarrays in Genomic Analysis
9. Overview of Differential Gene Expression by High-throughput Analysis
10. Aptamers: Powerful Molecular Tools for Therapeutics and Diagnostics
11. Chip-based Proteomics Technology
12. Infectomics Overview: Holistic and Integrative Studies of Infectious Diseases
13. The Drug Discovery Process
14. Structure-Based Drug Discovery
15. Protein Interaction-targeted Drug Discovery
16. Overview of Quantitative Structure–Activity Relationships (QSAR)

Index

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