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Diseases Book from C.H.I.P.S.

Molecular Epidemiology of Chronic Diseases
edited by Chris Wild

Molecular Epidemiology of Chronic Diseases crosses the disciplinary boundaries between laboratory scientists, epidemiologists, clinical researchers and biostatisticians and is accessible to all these relevant research communities in focusing on practical issues of application, rather than reviews of current areas of research.

Molecular Epidemiology of Chronic Diseases provides an easy-to-use, clearly presented handbook that allows epidemiologists to understand the specifics of research involving biomarkers, and laboratory scientists to understand the main issues of epidemiological study design and analysis.

Contents

  1. Introduction: why molecular epidemiology
  2. Study design
  3. Molecular epidemiological studies that can be nested within cohorts
  4. Family studies, haplotypes and gene association studies
  5. Individual susceptibility and gene-environment interaction
  6. Biomarker validation
  7. Exposure assessment
  8. Carcinogen metabolites as biomarkers
  9. Biomarkers of exposure: adducts
  10. Biomarkers of mutation and DNA repair capacity
  11. High-throughput techniques - genotyping and genomics
  12. Proteomics and molecular epidemiology
  13. Exploring the contribution of metabolic profiling to epidemiological studies
  14. Univariate and multivariate data analysis
  15. Meta-analysis and pooled analysis - genetic and environmental data
  16. Analysis of complex datasets
  17. Some implications of random exposure measurement errors in occupational and environmental epidemiology
  18. Bioinformatics
  19. Biomarkers, disease mechanisms and their role in regulatory decisions
  20. Biomarkers as endpoints in intervention studies
  21. Biological resource centres in molecular epidemiology: collecting, storing and analysing biospecimens
  22. Molecular epidemiology and ethics: biomarkers for disease susceptibility
  23. Biomarkers for dietary carcinogens: the example of heterocyclic amines in epidemiological studies
  24. Practical examples 2: hormones
  25. Aflatoxin, hepatitis B virus and liver cancer: a paradigm for molecular epidemiology
  26. Complex exposures - air pollution

Index

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Molecular Epidemiology of Chronic Diseases
edited by Chris Wild
2008 368 pages $129.00 + shipping
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