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Neurologic & Psychiatric Book from C.H.I.P.S.
The Molecular and Genetic Basis of Neurologic and Psychiatric Disease
Fourth Edition
by Roger N. Rosenberg

The Molecular and Genetic Basis of Neurologic and Psychiatric Disease is the most comprehensive and up-to-date review of the molecular and genetic basis of neurologic and psychiatric diseases.

Features

  • Experts provide a fresh, new assessment of recent molecular, genetic, and genomic advances
  • Offers new insights into disease pathogenesis
  • Describes the newest available therapies
  • Explores promising areas of therapeutic development
  • A Neurologic Gene Map describes the chromosome locus of all the genetic diseases and their gene product where known

The Molecular and Genetic Basis of Neurologic and Psychiatric Disease includes a companion website that features the fully searchable text online so the reader will have a fast, flexible multimedia library at their service.

Contents

General Concepts and Mechanisms of Disease

  1. Repeat Expansion Disorders: General Concepts and Mechanisms of Disease
  2. Mendelian, Nonmendelian, and Multigenic Inheritance and Complex Traits
  3. Selected Genetically Engineered Models Relevant to Human Neurodegenerative Disease
  4. Gene Mapping to Gene Targeting: Application of Mouse Genetics to Human Disease
  5. Genomics and the Human Genome Project
  6. Gene Therapy for Central Nervous System Disorders
  7. Emerging Ethical Issues in Neurology, Psychiatry, and the Neurosciences
  8. Genotype-Phenotype Correlations

Neurologic Diseases

  1. Down Syndrome
  2. Triplet Repeats: Genetics, Clinical Features, and Pathogenesis
  3. Prion Diseases
Part A: A Mitochondrial Disorders

  1. The Mitochondrial Genome
  2. Mitochondrial Disorders Due to Mutations in the Mitochondrial Genome
  3. Mitochondrial Disorders Due to Mutations in the Nuclear Genome
  4. Mitochondrial in Neurodegenerative Disorders

Part B: Peroxisomal Disorders

  1. Peroxisomal Disorders

Part C: Lysosomal Disorders

  1. Gaucher Disease
  2. The Niemann-Pick Diseases
  3. The GM2 Gangliosidoses
  4. Metachromatic Leukodystrophy and Multiple Sulfatase Deficiency: Sulfatide Lipidosis
....and chapters 21-29

Part D: Degenerative Disorders

  1. Alzheimer Disease
  2. Frontotemporal Dementias
  3. Genetics of Movement Disorders
  4. The Inherited Ataxias
  5. Canavan Disease
  6. The Hereditary Spastic Paraplegias

Parts E-I

Chapters 36-41

Part J: Myopathies

  1. Dystrophinopathies
  2. Limb-Girdle Muscular Dystrophies
  3. The Congenital Myopathies
...and chapters 45-49

Part K: Dermatologic and Brain Disorders

  1. The Phakomatoses
  2. Lipoprotein Disorders
  3. Apolipoprotein E: Structure and Function in Lipid Metabolism and Neurobiology
  4. Cerebrotendinous Xanthomatosis

Part L: Metabolic Disorders

  1. Disorders of Lipid Metabolism
  2. Glycogen Storage Diseases
  3. Disorders of Galactose Metabolism
  4. Inborn Errors of Amino Acid Metabolism
...and chapters 58-62

Parts M-O

Chapters 63-66

Part P: Vitamins

  1. Genetic and Dietary Influences on Life Span
  2. Vitamins: Cobalamin and Folate
  3. Disorders of Biotin Metabolism: Treatable Neurologic Syndromes

Psychiatric Disease

Chapters 70-76

A Neurologic Gene Map

  1. A Neurologic Gene Map

Index

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The Molecular and Genetic Basis of Neurologic and Psychiatric Disease
Fourth Edition
by Roger N. Rosenberg
2008 • 882 pages • $328.00 + shipping
Texas residents please add 6.75 % sales tax

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