Molecular Interventions in Lifestyle-Related Diseases provides insights on lifestyle factors relevant to health-related issues such as diet, alcohol consumption, cigarette smoking, and stress.

Features:

• Addresses the molecular basis and cellular effects of free-radical and lifestyle-related diseases
• Discusses free radicals, mechanisms of immune suppression and other disease factors related to oxidative stress
• Examines the therapeutic and prevention effects of specific nutrients, including flavonoids and polyphenols, and a whole range of phytonutrients

Contents

Free Radicals, Lifestyle-Related Diseases, and Their Protection

• Redox Regulation as an Underlying Factor in Health and Disease
• Diet and Lifestyle in Cancer Prevention
• The Gene Regulatory Mechanism of Thioredoxin and Thioredoxin Binding Protein-2/VDUP1 in Cancer Prevention
• Coenzyme Q10, Free Radicals, and Heart Disease
• Wine, Alcohol, and a Healthy Heart
• Diabetes Treatment by Alpha-Lipoic Acid: Modulation of Glucose Uptake and Adipocyte Differentiation
• The Mechanism of Immune Suppression by GIF and Cysteinylated MIF at Cys-60
• Role of Free Radicals in Cellular Damage and Its Modification by Antioxidants: Implications for Cancer Therapy
• Free Radical, Cigarette Smoke, and Health Scavenging Effects of Pycnogenol® on Free Radicals Generated from Cigarette Smoke and Its Detoxification Effects

Free Radicals, Brain Diseases, and Their Protection

• Free Radical Scavengers and Neuroprotection
• Oxidative Adaptation in Aging and Alzheimer's Disease: The Roles of Amyloid and Tau
• Coenzyme Q10 Stabilizes Mitochondria in Parkinson's Disease
• The In Vitro and In Vivo Molecular Mechanisms of Neuroprotection by the Major Green Tea Polyphenol, (-)-Epigallocatechin-3-gallate, with Special Reference to Parkinson's Disease
• Kainic-Acid-Induced Neurotoxicity: Involvement of Free Radicals
• Prevention of Cerebral Oxidative Stress Using Traditional Chinese Medicines: A Model of Antioxidant-Based Composite Formula
• Analysis of the Oxidative Stress State in Disease Development of Senescence-Accelerated Mouse

Nutraceuticals, Functional Foods, Micronutrients, and Pharmacological Interventions

• The Antioxidant Evolution: From Free Radical Scavenging to the Antioxidant Network and Gene Regulation by Flavonoids and Bioflavonoid-Rich Extracts from Pine Bark and Gingko Biloba Leaf
• New Horizons in Vitamin E Research
• Gastrointestinal Inflammatory Diseases: Role of Chemokine
• Oxidative Stress Involvement in Diabetic Nephropathy and Its Prevention by Astaxanthin
• Preventive and Therapeutic Effects of Plant Polyphenols through Suppression of Nuclear Factor-Kappa B
• Ascorbic Acid and Oxidative Damage to DNA: Interrelationships and Possible Relevance to Lifestyle-Related Diseases
• The Role of Lipid Peroxidation in Chromosomal DNA Fragmentation Associated with Cell Death Induced by Glutathione Depletion
• Antioxidant Properties of Select Indian Medicinal Plants in Relation to Their Therapeutic Effects
• Antioxidant Activity of Tendai-Uyaku Extract
• Detection of Active Oxygen Species in the Decomposition Process of Peroxovanadium (V) Complexes
• Structural Determination and Antioxidative Activity of Oxidation Products of Flavonoids with Reaction Oxygen Species
• Reactivity of Anthocyanin toward Reactive Oxygen and Reactive Nitrogen Species

Index

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