by J. M. Brown
Multimodal Concepts for Integration of Cytotoxic Drugs and Radiation Therapy summarizes the rationale and the preclinical data for combined treatment with ioinizing radiation and pharmaceutical agents, and comprises a series of disease-specific chapters in which the clinical results of combined modality treatment are presented.
Contents
Preclinical Part
- Biological Basis of Combined Radio- and Chemotherapy
- Combinations of Antimetabolites and Ionizing Radiation
- Combinations of Taxanes and Ionizing Radiation
- Combinations of Topoisomerase Inhibitors and Ionizing Radiation
- Combinations of Hypoxia-Targeting Compounds and Radiation-Activated Prodrugs with Ionizing Radiation
- Combinations of Platinum Compounds and Ionizing Radiation
- Combinations of Cytotoxic Drugs, Ionizing Radiation and Angiogenesis Inhibitors
- Combinations of Cytotoxic Drugs, Ionizing Radiation and EGFR Inhibitors
- Combinations of Cytotoxic Drugs, Ionizing Radiation and Mammalian Target of Rapamycin (mTOR) Inhibitors
- Combinations of Ionizing Radiation and Other Sensitizing Agents
- Radiotherapy and Tumor-Targeted Drug Delivery
Clinical Part
- Applications in Malignant Brain Tumors
- Applications in Head and Neck Cancer
- Applications in Esophageal and Gastric Cancer
- Novel Chemoradiation in Localized Pancreatic Cancer: Clinical Studies
- Applications in Lung Cancer
- Integration of Radiation Therapy and Systemic Therapy for Breast Cancer
- Applications in Rectal and Anal Cancer
- Concomitant Radiation and Chemotherapy in Muscle-Invasive Bladder Cancer
- Applications to Gynecological Cancers
- Early and Late Treatment-Induced Toxicity
- Feasibility of Combined Chemo- and Radiation Treatment in Elderly/Comorbid Patients
Index
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