Nanoparticle Technology for Drug Delivery describes methods for the manufacture of nanoparticles including milling, homogenization, and supercritical fluid technology.

Features:

• Offers technologies for stabilizing nanoparticles
• Presents drug delivery applications of nanoparticles by parenteral and oral routes
• Describes the latest advances in the application of nanoparticles for drug delivery to the brain and eye
• Summarizes the recent developments in the use of nanoparticles for gene delivery
• Details the characterization of nanoparticles at the material and physicochemical level
• Provides nanoparticles technologies for the delivery of conventional and contemporary drugs
• Highlights the efficacy and potential toxicity of nanoparticles

Contents

Technologies for Nanoparticle Manufacturing

1. Fundamentals of Drug Nanoparticles
2. Manufacture of Nanoparticles by Milling and Homogenization Techniques
3. Supercritical Fluid Technology for Particle Engineering
4. Polymer or Protein Stabilized Nanoparticles from Emulsions

Nanoparticle Characterization and Properties

5. Physical Characterization of Nanoparticles
6. Nanoparticle Interface: An Important Determinant in Nanoparticle-Mediatel Drug/Gene Delivery
7. Toxicological Characterization of Engineered Nanoparticles

Drug Delivery Applications of Nanoparticles

8. Injectable Nanoparticles for Efficient Drug Delivery
9. Polymeric Nanoparticles for Oral Drug Delivery
10. Brain Delivery by Nanoparticles
11. Nanoparticles for Ocular Drug Delivery
12. DNA Nanoparticle Gene Delivery Systems

Clinical, Ethical, and Regulatory Issues

13. Nanotechnology and Nanoparticles: Clinical, Ethical, and Regulatory Issues

Index

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