Nucleic Acid Testing for Human Disease describes various techniques including target and signal amplification-based NAT procedures, microarrays, bead-based multiplex assays, in situ hybridization, and SNP techniques.

Features:

• Features contributions from leading researchers in academia, clinical testing labs, and industry
• Describes NAT testing technologies and related clinical applications
• Covers techniques such as target and signal amplification-based procedures and bead-based multiplex assays
• Discusses specific applications of NATs to human disease diagnosis and treatment
• Explores future directions in the field

Contents

Nucleic Acid Diagnostic Technology

• Target Amplification-Based Techniques
• Signal Amplification-Based Techniques
• Microarrays: Human Disease Detection and Monitoring
• Bead-Based Flow Systems: From Centralized Laboratories to Genetic Testing in the Field
• In situ Hybridization
• SNP Detection Techniques
• RNA Expression Profiling
• Evolution of the Molecular Microbiology Laboratory

Disease Applications of NAT Tests

• Bacterial STDs
• Sexually Transmissible Viral Pathogens: The Human Papillomaviruses and Herpes Simplex Viruses
• Blood-Borne Viruses in Clinical and Diagnostic Virology
• Molecular Methods for the Diagnosis of Fungal Infections
• Molecular Diagnostic Approaches in Infectious Disease. Cancer Detection and Prognosis
• Common Inherited Genetic Disorders
• Bridging the Gap Between Analytical and Clinical Validation
• Future Perspectives on Nucleic Acid Testing

Index

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