Nutrient-Gene Interactions in Cancer brings together leading authorities in the field who provide an overview and look specifically at the mechanisms known to underlie each nutrient and gene interaction.

Features:

• Provides the latest epidemiological evidence on the interactions between nutrients and gene polymorphisms affecting cancer development
• Describes interactions that affect colorectal, breast, lung, prostate, liver, and other gastroenterological cancers, as well as hematologic malignancies
• Gives an overview of nutrient-gene interaction mechanisms and explores specific biomarkers
• Offers striking examples of the interaction between genetics, epigenetics, and nutrition in many different types of cancer

Contents

• Nutrients and Gene Interactions in Cancer
• Candidate Mechanisms for Interactions between Nutrients and Genes
• Biomarkers for Nutrient-Gene Interactions
• Interaction between Folate and Methylene-tetrahydrofolate Reductase (MTHFR) Gene in Cancer
• Genetic Variability in Folate-Mediated One-Carbon Metabolism and Cancer Risk
• S-Adenosylmethionine and Methionine Adenosyltransferase Genes
• Effects of Carotenoid Supplementation on Signal Transduction Pathways: Significance in Lung Cancer Prevention
• The Actions of the Vitamin D Receptor in Health and Malignancy; Polymorphic Associations and Gene Regulatory Actions
• The Role of Alcohol Dehydrogenase Polymorphism in Alcohol-Associated Carcinogenesis
• Genetic Polymorphism of N-Acetyltransferase Genes as Risk Modifiers of Colorectal Cancer from Consumption of Well-Done Meat
• Ferritin and Serine Hydroxymethyltransferase
• Brassica-Gene Interactions and Cancer Risk

Index

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