Medical Science Book from C.H.I.P.S.

Operative Neuromodulation
Volume 1
Functional Neuroprosthetic Surgery
edited by D. E. Sakas

Operative Neuromodulation describes techniques and procedures applied in internal contact with non-neural tissues surrounding the nervous system (dura or cerebrospinal fluid), as in the case of epidural stimulation for pain or intrathecal drug application for the treatment of spasticity and pain.

In addition, coverage also includes a special section on non-invasive functional neuroprosthetic systems, which are usually applied by transcutaneous contact with the nervous system.

Operative Neuromodulation describes the neural networks involved and the appropriate surgical approaches, provide clinical guidelines and technical descriptions of implanted devices, and offer proposals for refinements as well as personal views on future prospects of the field.



  • Management of Chronic Severe Pain: Spinal Neuromodulatory and Neuroablative Approaches
  • Intrathecal Opioids for intractable Pain Syndromes
  • Management to Chronic Back and Leg Pain by Intrathecal Drug Delivery
  • Drug-Enhanced Spinal Stimulation for Pain: A New Strategy
  • Neurosurgical Pain Therapy with Epidural Spinal Cord Stimulation
  • Spinal Cord Stimulation for Pain: A New Strategy
  • Spinal Cord Stimulation for Failed Back Surgery Syndrome and Other Disorders
  • Spinal Cord Stimuation for the Treatment of Chronic Non-Malignant Pain
  • Dual Electrode Spinal Cord Stimulation in Chronic Leg and Back Pain
  • Factors Affecting Spinal Cord Stimulation Outcome in Chronic Benign Pain with Suggestions to Improve Success Rate
...and more

Spasticity and Related Disorders

  • The Phenomemom of Spasticity: A Pathophysiological and Clinical Introduction to Neuromodulation Therapies
  • Intrathecal Baclofen in Current Neuromodulatory Practice: Established Indications and Emerging Applications
  • Intrathecal Baclofen Therapy: Indications, Pharmacology, Surgical Implant, and Efficacy
  • Intrathecal Baclofen in the Treatment of Spasticity
  • Intrathecal Baclofen Therapy in Patients with Severe Spasticity
  • Intrathecal Antispastic Drup Application with Implantable Pumps: Results of a 10 Year Follow-up Study
  • Intrathecal Baclofen for the Treatment of Spasticity
  • Management of Spasticity in Multiple Sclerosis by Intrathecal Baclofen
  • Surgical Management of Spasticity of Cerebral Origin in Children
  • Efficacy of Intrathecal Baclofen Delivery in the Management of Severe Spasticity in Upper Motor Neuron Syndrome
...and more

Cardiovascular, Cerebrovascular and Respiratory Disorders

  • Epidural Spinal Cord Stimulation in Lower Limb Ischemia
  • Spinal Cord Stimulation in the Treatment of Chronic Critical Limb Ischemia
  • Cervical Spinal Cord Stimulation in Cerebral Ischemia
  • Spinal Cord Stimulation in the Treatment of Post-Stroke Patients: Current State and Future Directions
  • Neurostimulation for Refractory Angina Pectoris
  • Diaphragm Pacing with a Spinal Cord Stimulator: Current State and Future Directions
  • Neuroprostheses for Management of Dysphagia Resulting from Cerebrovascular Disorders

Bladder, Bowel, and Sexual Disorders

  • Management and Rehabilitation of Neuropathic Bladder in Patients with Spinal Cord Lesion
  • Sacral Neuromodulation as a Function Treatment of Bladder Overactivity
  • Dorsal Rhizotomy Combined with Anterior Sacral Root Stimulation for Neurogenic Bladder
  • Surgical Therapy of Neurogenci Detrusor Overactivity in Paraplegic Patients by Sacral Deafferentation and Implant Drivin Micturition by Sacral Anterior Root Stimulation: Methods, Indications, Results, Complications, and Future Prospects
  • Sacral Neuromodulation in the Treatment of Defecation Disorders
  • Sacral Nerve Stimulation for Fecal Disorders: Evolution, Current Status, and Future Directions
  • Neurally Augmented Sexual Function
  • Neuromodulatory Approaches to Chronic Pelvic Pain and Coccygodynia

Functional Electrical Stimulation

  • Neuromodulation by Functional Electrical Stimulation of Limb Paralysis after Stroke
  • Neuromodulation of Effects of Upper Limb Motor Function and Shoulder Range of Motion by Functional Electric Stimulation
  • Neuromodulation of Lower Limb Monoparesis: Functional Electrical Therapy of Walking
  • FES Cycling
  • Reconstruction of Upper Limb Motor Function Using Functional Electrical Stimulation


  • Neural Prostheses in Clinical Practice: Biomedical Microsystems in Neurological Rehabilitation
  • Neuroprosthetics of the Upper Extemity—Clinical Application in Spinal Cord Injury and Challenges for the Future
  • Neural Prostheses and Biomedical Microsystems in Neurological Rehabilitation
  • Restoration of Neurological Functions by Neuroprosthetic Technologies: Future Prospects and Trends Towards Micro-, Nano-, and Biohybrid Systems

Emerging Applications

  • The Role of Spinal Cord Stimulation in the Management of Patients with Brain Tumors
  • Dorsal Column Stimulation for Persistent Vegetative State
  • Relationship Between Intrathecal Baclofen and the Central Nervous System
  • Robot-aided Rehabilitation of Neural Function in the Upper Extremities
  • Experimental Therapies for Chronic Pain


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Operative Neuromodulation
Volume 1
Functional Neuroprosthetic Surgery
edited by D. E. Sakas

2007 • 234 pages • $258.00 + shipping
Texas residents please add 6.75 % sales tax

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