Medical Book from C.H.I.P.S.

Operative Neuromodulation
Volume 2
Neural Networks Surgery
by D. E. Sakas

Operative Neuromodulation describes the techniques and procedures applied by direct contact with the central nervous system or cranial nerves, in order to modulate the function of neural networks as in the case of motor cortext stimulation for pain.

Operative Neuromodulation:

  • describes the neural networks involved and the appropriate surgical approaches
  • provides clinical guidelines and technical descriptions of implanted devices,
  • offers proposals for refinements as well as personal views on future prospects of the field

Operative Neuromodulation also describes the techniques and procedures applied in deeply located structures inside the nervous system, in order to alter the function on specific networks as in the case of deep brain stimulation for Parkinson’s disease.


1. Pain

  • Management of Chronic Severe Pain: Cerebral Neuromodulatory and Neuroablative Approaches
  • Extradural Cortical Stimulation for Central Pain
  • Motor Cortex Stimulation for Neuropathic Pain
  • Motor Cortex Stimulation for Chronic Non-Malignant Pain: Current State and Future Prospects
  • Stimulation of Primary Motor Cortex for Intractable Deafferentation Pain
  • Cathodal, Anodal or Bifocal Stimlulation of the Motor Cortex in the Management of Chronic Pain?
...and more

2. Movement disorders

  • Surgical Considerations in Movement Disorders: Deep Brian Stimulation, Ablation and Transplantation
  • Deep Brain Stimulation and Chemical Neuromodulation: Current Use and Perspectives for the Future
  • GDNF Delivery for Parkinson's Disease
  • Neuronal Networks of the Basal Ganglia and the Value of Recording Field Potentials from Them
  • Technical Aspects and Considerations of Deep Brain Stimulation Surgery for Movement Disorders
  • Deep Brain Stimulation for Parkinson's Disease
...and more

3. Epilepsy

  • Electrical Stimulation Devices in the Treatment of Epilepsy
  • Brain Stimulation for Epilepsy
  • Clinical Experience with Vagus Nerve Stimulation and Deep Brain Stimulation in Epilepsy
  • Vagus Nerve Stimulation: Indications and Limitations
  • Vagus Nerve Stimulation for Intractable Epilepsy: Outcome in Two Series Combining 90 Patients
  • Electrical Stimulation and Gene-based Neuromodulation for Control of Medically-Refractory Epilepsy
  • Rationale, Mechansims of Efficacy, Anatomical Targets and Future Prospects of Electrical Deep Brain Stimulation for Epilepsy
...and more

4. Psychiatric Disorders

  • Neurosurgery for Psychiatric Disorders: From the Excision of Brain Tissue to the Chorinic Electical Stimulation of Neural Networks
  • Behavioural and Physiological Effects of Electrical Stimulation
  • Neuromodulation of the Inferior Thalamic Peduncle for Major Depression and Obsessive Compulsive Disorder
  • Chronic High Frequency Stimulation of hte Posteromedical Hypothalamus in Facial Pain and Syndromes and Behaviour Disorders
  • Vagus Nerve Stimulation for Depression: Rationale, Anatomical, and Physiological Basis of Efficacy and Future Prospects

5. Hearing disorders

  • Experimental and Clinical Aspects of the Efferent Auditory System
  • Functional Outcome of Auditory Implants in Hearing Loss
  • Auditory Brainstem Implants: Current State and Future Directions with Special Reference to the Subtonsillar Approach for Implantation
  • Auditory Brainstem Implants: Past, Present, and Future Prospects
  • Twenty-Five Years of Auditory Brainstem Implants: Perspectives
  • Auditory Cortex Stimulation for Tinnitus

6. Visual disorders

  • Implantable Visual Prostheses
  • Restoring Visual Perception Using Microsystem Technologies: Engineering and Manufacturing Persepectives
  • A Neuroprosthesis for Restoring Sight
  • Towards the Bionic Eye—The Retinal Implant: Surgical, Opthalmological and Histopathological Perspectives

7. Computational neuromodulation

  • Motor Cortex Stimulation: Role of Computer Modeling
  • Computational Models Simulating Electrophysiological Activity in the Basal Ganglia
  • Computational Perspectives on Neuromodulation of Aging


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Operative Neuromodulation
Volume 2
Neural Networks Surgery
by D. E. Sakas

2007 • 588 pages • $318.00 + shipping
Texas residents please add 6.75 % sales tax

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