Organic Synthesis with Carbohydrates provides a broad understanding of the use of carbohydrates in organic synthesis at the postgraduate level.

Emphasis is placed on retrosynthetic analysis, with discussion of why a particular synthetic route has been chosen, and mechanistic explanations are provided for key and novel reactions. Wherever possible, points of general significance to organic synthesis are highlighted. Selected experimental conditions and reaction details are incorporated to ensure that information can be utilized in research.

The book is extensively referenced.

Contents

Structure and Synthesis of Saccharides and Glycoproteins

1. Mono- and oligosaccharides: structure, configuration and conformation
2. Protecting groups
3. Functionalized saccharides
4. Oligosaccharide synthesis
5. The chemistry of O- and N-linked glycopeptides

Natural Product Synthesis from Monosaccharides

6. (-)-Echinosporin
7. (+)Zaragozic acid C
8. (+)-Neocarzinostatin
9. (+)-Castanospermine
10. (-)-Silphiperfolene
11. (-)-Allosamizoline
12. (-)-Reiswigin A
13. (-)-Octalactin A
14. (-)-ACRL toxin I
15. (+)-Gasbosine E
16. (-)-Augustamine and (-)-amabiline
17. (-)-FK506
18. (3S, 5S)-5-Hydroxypiperazic acid

Index

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