Oxidative Stress and Age-Related Neurodegeneration brings together expert researchers involved with recent developments across a variety of fields.

Features:

• Covers the most recent developments in age-related neurodegenerative disorders
• Describes experimental evidence supporting the role of oxidative stress in these disorders
• Explores the effects of oxidative stress and how they can be addressed
• Discusses the similarities and differences between aging and neurodegeneration in terms of susceptibility to oxidative stress
• Examines the role of specific natural micronutrients and antioxidants

Contents

• Proteomics Identification of Oxidatively Modified Proteins in the Alzheimer's Disease Brain and Models Thereof: Insights into Potential Mechanisms of Neurodegeneration
• Direct Evaluation of Alzheimer's Disease-Specific Oxidative Stress with Multiphoton Microscopy
• Ginkgo biloba Extract and Alzheimer's Disease: Is the Neuroprotection Explained Merely by the Antioxidant Action
• Mitochondrial Nutrients: Reducing Mitochondrial Decay to Delay or Treat Cognitive Dysfunction, Alzheimer's Disease, and Parkinson's Disease
• Reactive Oxygen and Nitrogen Species: Weapons of NeuronalDestruction
• Amyloid ß and Tau in Alzheimer's Disease: What is the Neuropathology Trying to Tell Us
• Antioxidant Therapies in the Prevention and Treatment of Alzheimer Disease
• F2-Isoprostanes as Biomarkers of Late Onset Alzheimer's Disease
• Aspirin and Alzheimer's Disease Protection
• The Disposition of Lipid-Derived Carbonyls in Alzheimer's Disease
• Methionine Sulfoxide Reductase System: Possible Roles in Protection against Neurodegenerative Diseases
• Nutritional Antioxidant Enrichment and Improved Cognitive Function in Canines
• Green Tea and Resveratrol as Protective Agents against Neurotoxins
• Oxidative Stress and AßPP Processing
• Apple Phenolics and Alzheimer's Disease
• Effects of Nicotine in Models of Alzheimer's Disease
• The Essentiality of Iron Chelation in Neuroprotection: A Potential Role of Green Tea Catechins
• Ginkgo biloba Extract Egb761 Extends Life Span and Attenuates H2O2 Levels in a Caenorhabditis elegans Model of Alzheimer's Disease
• Cysteine Proteases as ß-Secretases for Aß Production in the Major Regulated Secretory Pathway of Neurons: Implications for Therapeutic Strategies in Alzheimer's Disease
• The Molecular Mechanism of the Neuroprotective Action of Antioxidants Compared with the Anti-Parkinson Drug, Rasagiline
• Temporal Primacy of Oxidative Stress in the Pathological Cascade of Alzheimer Disease
• Age-Related Neuronal and Behavioral Deficits are Improved by Polyphenol-Rich Blueberry Supplementation
• Amyloid-ß Peptide, a Therapeutic Target for Alzheimer's Disease
• Nutrition, Brain Aging, and Alzheimer's Disease
• Interaction between Dietary and Genetic Deficiencies in the Modulation of Homocysteine Elimination
• Nutriproteomics Approach to Understanding Dementia-Relevant Brain Protein Changes in Response to Grape Seed Extract, a Dietary Antioxidant

Index

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