A comprehensive review of peripheral pain mechanisms, Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management provides a unique resource that brings together a body of knowledge that was previously widely dispersed.

Coverage includes:

• The latest discoveries by leading researchers relating to the function of various ion channels and receptors in the peripheral nervous system
• Novel delivery techniques
• An appendix listing currently available topical analgesic medications

Contents

Part I: Peripheral Mechanism in Clinical Pain Conditions

1. Role of Peripheral Mechanisms in Craniofacial Pain Conditions
2. Role of Peripheral Mechanisms in Spinal Pain Conditions

Part II: Specific Receptor Targets for Peripheral Analgesics

3. Voltage-Gated Sodium Channels in Peripheral Nociceptive Neurons as Targets For the Treatment of Pain
4. Potassium Channels
5. Voltage-Gated Calcium Channels as Targets for the Treatment of Chronic Pain
6. Adenosine Receptors
7. Acid-Sensing Ion Channels and Pain
8. Vanilloid (TRPV1) and Other Transient Receptor Potential Channels
9. Glutamate Receptors
10. Serotonin Receptors
11. Adrenergic Receptors
12. Cholinergic Receptors and Botulinum Toxin
13. Cannabinoids and Pain Control in the Periphery
14. Opioid Receptors
15. Calcitonin Gene-Related Peptide and Substance P
16. Role of Somatostatin and Somatostatin Receptors in Pain
17. Cytokines (Tumor Necrosis Factor, Interleukins) and Prostaglandins
18. Neurotrophic Factors and Pain

Part III: Delivery Systems

19. Topical and Systemic Drug Delivery Systems Targeted Drug Therapy
20. Gene Therapy for Pain
21. Topical Analgesics

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ORDER NOW Peripheral Receptor Targets for Analgesia Novel Approaches to Pain Management edited by Brian E. Cairns 2009 • 541 pages • $144.00 + shipping Texas residents please add 6.75 % sales tax