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Pharmaceutical Dosage Reference from C.H.I.P.S.

Pharmaceutical Dosage Forms
Disperse Systems: Volume 1
Pharmaceutical Dosage Forms
Disperse Systems: Volume 2
Pharmaceutical Dosage Forms
Disperse Systems: Volume 3

Pharmaceutical Dosage Forms
Disperse Systems
Volume 1 Second Edition
edited by
Herbert A. Lieberman

Entirely updating and expanding the First Edition of these well-received references, Disperse Systems Volume 1 offers new data on:

  • Light scattering techniques and improvements in microscopy
  • An enlarged description of emulsification
  • Novel applications of colloids and pseudolatex polymer dispersions
  • New discussions on micellar shape and the concept of the critical packing parameter
  • Updates analyses of regulatory and compendial concepts of drug products and their safety
  • A rewritten and expanded section on bioavailability of disperse dosage forms
  • And more!

Contains hundreds of bibliographic citations, tables, drawings, photographs, and equations.

Contents

  1. Introduction
    Free Energy Considerations
    Stabillity Considerations
    Protocols

  2. Theory of Suspensions
    Classification of Dispersed Systems
    Particle Properties
    The Solid-Liquid Interface
    Preparation
    Stabilization
    Rheological Aspects
    Effect of Additives

  3. Theory of Emulsions
    General Aspects of Emulsions
    Stability of Two-Phase Emulsions
    Stability of Three-Phase Emulsions

  4. Theory of Colloids
    Electrostatic stabilization of Latexes
    Steric Stabilization of Latexes
    Preparation of Latexes by Direct Emulsification

  5. Rheological and Mechanical Properties of Dispersed Systems
    Fundamentals
    Elasticity and Viscosity
    Viscometry
    Rheology of Dispersed Systems

  6. Surfactants
    Definitions and General Proerties of Surfactants
    Physical Description of Surfactants in Solution
    Chemical Description of Surfactants
    Special Topics
    Biological Effects of Surfactants
    Use of Surfactants in Drug Products
    Effect of Surfactants on Drug Efficacy

  7. Viscosity-Imparting Agents in Disperse Systems
    Polymer Solution Rheology
    Sedimentation Control in Disperse Systems
    Viscosity Changes During Product Aging
    Flocculation and Deflocculation Phenomena
    Excipient Compatability
    Polymer Selection
    Viscosity-Building Substances
    Sample Formulations

  8. Bioavailability of Disperse Dosage Forms
    Formulation Factors Affecting Drug Release from Disperse Systems
    Principles of Drug Release from Disperse Systems
    In Vitro-In Vivo Correlations
    Physiological Factors Affecting Bioavailability
    Methods of Assessing Drug Bioavailability
    In Vivo Bioavailability Assessment

  9. Preservation of Dispersed Systems
    General Characteristics
    Microbial Contamination
    Preservatives
    Effects of Product Ingredients on Preservative Activity
    Evaluation of Preservative Efficacy
    Future Trends

  10. Experimental Design, Modeling, and Optimization Strategies for Product and Process Development
    Deterministic Modeling
    Stochastic Modeling

Index

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Pharmaceutical Dosage Forms: Disperse Systems
Volume 1 Second Edition

edited by Herbert A. Lieberman
532 pages $228.95 + shipping
Texas residents please add 6.75 % sales tax

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