Pharmaceutical Isothermal Calorimetry discusses the application of isothermal calorimetric techniques to challenges encountered during the rational design and development of novel drugs and drug delivery systems.

Features:

• Provides an in-depth user guide that offers step-by-step instruction on experimental set-up, calibration, and new methods of data analysis
• Presents best practices in experimentation and discusses the principles of calibration in reference to the latest IUPAC guidelines
• Simplifies data analysis and interpretation and covers recent methods by pioneering researchers on the topic
• Utilizes case studies to highlight specific applications discussed in the text
• Covers current techniques in stability testing, screening, and storage temperature stability assessment

Contents

1. The Principles of Calorimetry
2. Good Experimental Practice
3. Quantitative Data Analysis
4. The Role of Calorimetry in Pre-Formulation Studies
5. Lead Compound Optimization
6. Investigation of the Amorphous State
7. Stability Assessment
8. Future Developments and Areas of Application

Index

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