Postmenopausal Osteoporosis has in-depth sections on the pathogenesis, epidemiology, and diagnosis of osteoporosis.

Features:

• Published in association with International Menopause Society
• Comprehensive
• Focus on therapy
• High-class, international authorship

Contents

Introduction

1. Magnitude and impact of osteoporosis and fractures
2. Impact of osteoporosis on quality of life and quality of life on osteoporosis: rationale and methodology for accurate assessment

Gonadal Steroids and The Pathogenesis of Osteoporosis

3. Peptide hormones and osteocyte growth factors
4. Steroids as regulators of osteoblastic function
5. Steroids and the regulation of osteoclastic bone resorption
6. Calcium and vitamin D: regulation of mineral homeostasis

Epidemiology

7. Genetic determinates of bone mass
8. Bone mineral acquisition during infancy & adolescence
9. Style of life, physical activity and nutritional factors
10. Postmenopausal osteoporosis & dental health

Diagnosis

11. Bone densitometry and radiology
12. Assessment of bone quality. Clinical, hormonal and biochemical evaluation.
13. New techniques for the non-invasive assessment of bone quality
14. Bone ultrasound

Pharmacological Prevention and Treatment

15. Awareness of osteoporosis and related treatments
16. Intervention thresholds for osteoporosis
17. Vitamin D and calcium supplements
18. Estrogen dose response in bone density and bone histology
19. Effects of oral contraceptive preparation on hone health
20. Hormone replacement therapy
21. New physiologic approach to prevention of postmenopausal osteoporosis
22. Selective estrogen receptor modulators
23. Bisphosphonates in the management of osteoporosis
24. Phytoestrogens: food or drug?
25. Tibolone
26. Understanding the role of aromatizable androgens in bone-sparing

Specific Aspects of Selected Therapies

27. Strontium ranelate: a new first-line treatment for patients
28. Reconciling risks and benefits of hormone replacement therapy in a single outcome: the QALY approach
29. Prevent, treat and maintain: how to optimize the management of postmenopausal osteoporosis
30. Transdermal hormone therapy: effects on bone
31. Progestogens and bone
32. Effect of different dose options of continuous combined hormone therapy on bone and bone marker N-terminal propeptide of type I procollagen: results from a long-term study on Finnish postmenopausal women
33. The use of alendronate in osteoporosis treatment: 10-year experience

Index

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