Quantitative Imaging Tools for Lung Cancer Drug Assessment presents chapters written by leading clinical researchers in the field of lung cancer, where high resolution 3-D imaging technology appears to hold the greatest near-term promise, as well as contributions from recognized experts in CAD, medical information technology systems, regulatory procedure, x-ray standards development, and clinical trial design.

These expert contributors discuss the current state of the art and provide a road map for directing further research in lung cancer as well as other organ systems.

Contents

1. Incorporating Imaging into Drug Development: An Industry Perspective
2. Developing Imaging Tools for Drug Development: Critical Technology, Clinical Data and Regulatory
3. Quantitative Imaging in CT Lung Cancer Drug Development and Evaluation
4. Volumetric CT Imaging for Response Assessment in Lung Cancer: A Platform for Translational Research
5. Emerging Radiological Software Standards and Development Technologies: Impact on Clinical Translation and Trials
6. Statistical Considerations Underlying Therapeutic Response Criteria for Lung Cancer: A Review in the Context of Emergence of Multi-Slice CT Scanner and Computer Assisted Diagnostic Algorithm for Volumetric Assessment
7. Programs Supporting Quantitative Imaging in Biomedicine at the National Institute for Standards and Technology

Appendixes:

• Evolving Imaging Resources: Public Access Databases (Laurence Clarke).
• Biomedical Imaging Archive Network (Thomas M. Baer and James L. Mulshine).
• Developing CT Image-Processing Tools to Accelerate Progress in Lung Cancer Drug Development

Index

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