Samter's
Immunologic Diseases
Sixth Edition

2 Volume Set w/ CD-ROM
edited by K. Frank Austen, Michael M. Frank, John P. Atkinson and Harvey Cantor

The thoroughly updated Sixth Edition of this classic two-volume work continues to provide a comprehensive overview of immunology, its clinical applications, immunopathology, and allergy.

A text revised and updated throughout facilitates an understanding of the host mechanisms in immunologic diseases. The strength of this text is its clinically oriented emphasis on immunologic diseases and differential approach to symptoms and syndromes.

Samter's Immunologic Diseases features an increased clinical coverage and is an essential reference for all clinical immunologists, rheumatologists, and allergists. It includes a CD-ROM bound in the back of the book.

Contents

Volume 1

1. Recognition: Innate and Adaptive Immunity
   1. Innate Immunity: Linkages to Adaptive Responses
   2. Architecture of the Immune System
   3. MHC: Structure and Function
   4. T-Cell Antigen Receptors
   5. T-Cell Biology and the Thymus
   6. Antigen Processing and Presentation
   7. Immunogenicity and Antigenicity
   8. Lymphocyte Signaling
   9. T-Lymphocyte Activation, Costimulation, and Tolerance: Signals, Mechanisms, and Clinical Applications
   10. Cytokines and Type 1 Immunity
   11. Cytokine Regulation of Type 2 Immunity
   12. Apoptosis and the Immune Response
   13. Antibodies and Their Receptors
   14. Biology of B Cells
   15. Adhesion Molecules
   16. Chemokines and Chemokine Receptors
   17. Hematopoietic Cytokines

2. Effector Mechanisms: Innate and Adaptive
   18. T-Lymphocyte Effector Activity
   19. Natural Killer Cells
   20. Neutrophils
   21. Monocytes and Macrophages
   22. Eosinophils
   23. Basophils
   24. Biology of the Mast Cell
   25. Immune Complexes
   26. Complement System
   27. Arachidonic Acid Pathways

3. Primary Immunodeficiencies
   28. Primary Immunodeficiencies of Lymphocytes
   29. Phagocyte Disorders
   30. Complement in Disease: Inherited and Acquired Complement Deficiencies

4. Proliferation Disorders of Immunologic Cells
   31. Lymphocyte Lymphomas and Hodgkin's Disease
   32. Multiple Myeloma
   33. Macroglobulinemia
   34. Amyloidosis
   35. Eosinophilia
   36. Mastocytosis

   Volume 2

5. Systemic Diseases
   37. Rheumatoid Arthritis
   38. Juvenile Rheumatoid Arthritis
   39. Systemic Lupus Erythematosis
   40. Sjorgen's Syndrome
   41. Systemic Sclerosis (Scleroderma)
   42. Idiopathic Inflammatory Myopathies: Dermatomyositis, Polymyositis, and Related Disorders
   43. The Spondyloarthropathies
   44. Rheumatic Fever and Other Cardiovascular Disease
   45. Vasculitis
   46. Antiphospholipid Syndrome
   47. Sarcoidosis

6. Organ-Specific Diseases
   48. Diabetes Mellitus
   49. Autoimmune Thyroid Disease, Addison Disease, and Autoimmune Polyglandular Syndromes
   50. Immunologic Renal Disease
   51. Myasthenia Gravis
   52. Autoimmune Blistering Mucocutaneous Diseases
   53. Immune Function in Ocular Inflammatory Disease
   54. Autoimmune Hepatobiliary Diseases
   55. Immunological Diseases of the Gastrointestinal Tract
   56. Multiple Sclerosis
   57. Autoimmune Hemolytic Anemia
   58. Immune Thrombocytopenia
   59. Blood Groups, Immunologic Hazards of Transfusion, and Hemolytic Disease of the Newborn
   60. Immunological Aspects of Fertility and Infertility

7. Allergic Diseases
   61. Allergens
   62. Genetics of Allergic Disease
   63. Allergic Rhinitis
   64. Anaphylactic Syndrome
   65. Asthma
   66. Urticaria and Angioedema: Pathogenesis, Assessment, and Treatment
   67. Atopic Dermatitis
   68. Allergic Reactions to Foods
   69. Insect Venom Allergy
   70. Immunologic Lung Disease
   71. Allergic Contact Dermatitis
   72. Allergic Reactions to Drugs
   73. Natural Rubber Latex Allergy

8. Evasion, Activation, and Ineffective Immunity
   74. Human Immunodeficiency Virus Infection
   75. Epstein-Barr Virus
   76. Tuberculosis and Leprosy
   77. Cryopathies: Cryoglobulins and Cryofibrinogenemia
   78. Viruses
   79. Lyme Disease
   80. Parasitic Diseases
   81. The Immunocompromised Host
   82. Aging and the Immune System

9. Transplantation
   83. Hematopoietic Stem Cell Transplantation
   84. Tissue and Solid Organ Allograft Rejection
   85. Immunology of Xenotransplantation

10. Therapeutic Immunology
    86. Calcineurin as a Therapeutic Target
    87. T-Cell Antigen and Costimulatory Receptors as Therapeutic Targets
    88. Cytokines and Cancer Immunotherapy
    89. Anti-TNF-α Therapy in Rheumatoid Arthritis and Other Diseases
    90. Use of Intravenous Immunoglobulin
    91. Monoclonal Antibody Therapy
    92. Drugs that Modulate the Immune Response
    93. New Approaches to Vaccine Development

Appendices
Index

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