Seafood Toxins Handbook from C.H.I.P.S.

Seafood and Freshwater Toxins
Pharmacology, Physiology, and Detection
Second edition
edited by Luis M. Botana

Seafood and Freshwater Toxins: Pharmacology, Physiology, and Detection, Second edition provides current knowledge from several perspectives. Incorporating toxicology, chemistry, ecology, and economics, the book covers the biological aspects of the bloom and the effects and actions of each toxin with emphasis on human response.

This edition includes more information on detection and analysis, toxicological information on previously little known toxins, and food safety issues.

Incorporating Pharmacological, Legal, and Economic Aspects, this book:

  • Provides general information on risk assessment and analytical techniques
  • Covers several categories of toxins by function and biomechanism
  • Considers potential pharmacological applications and the use of toxins as precursors to therapeutic drugs
  • Highlights the legal and economic perspectives of toxic incidence in industrial activity and international regulation and monitoring programs
  • Describes new toxins by their individual chemical structure, ecobiology, metabolism, detection methods, determination, pharmacology, and toxicology


General Considerations

  • Risk Assessment of Marine Toxins
  • Analysis of Marine Toxins – Techniques, Method Validation, Calibration Standards and Screening Methods

The Epidemiological Impact of Toxic Episodes

  • Diarrheic Toxins
  • Neurotoxic Toxins

    Diversity of Marine Toxins as Pharmacological Tools

    • Calcium Channels for Exocytosis: Functional Modulation with Toxins
    • The Mouse Bioassay as a Universal Detector

    Paralytic Shellfish Poisoning (PSP)

    • Metabolism of Paralytic Shellfish Toxins Incorporated into Bivalve
    • Chemical Analysis
    • Pharmacology and Toxicology: Biological Detection Methods

    Diarrheic Episodes: Phosphatase Inhibitors

    • Chemistry, Metabolism, Chemical Analysis of OA Group Toxins
    • Pharmacology and Toxicology

    Lipophyllic Toxins: Non-phosphatase Inhibitors

    • Planktonic Dinoflagellates which Produce Polyether Toxins of the Old “DSP Complex”


    • Chemistry, Metabolism, Chemical Analysis
    • Pharmacology and Mechanism of Action: Biological Detection
    • Toxicology of the Yessotoxins


    • Chemistry, Metabolism, and Chemical Detection Methods of Pectenotoxins
    • Pharmacology of Pectenotoxins
    • Toxicology of Pectenotoxins

    Domoic Acid Intoxication

    • Ecobiology of ASP Producing Diatoms
    • Domoic Acid: Detection Methods, Pharmacology and Toxicology

    Non-PSP Neurotoxic Episodes

    • The Ecobiology of the Brevetoxin, Ciguatoxin and Cyclic Imine Producers

    Ciguatera Toxins

    • Ciguatera Toxins: Chemistry, Toxicology and Detection


    • Maitotoxin: a Unique Pharmacological T ool for Elucidating Ca2+-Dependent Mechanisms


    • The Molecular and Integrative Basis to Brevetoxin Toxicity
    • Detection of Brevetoxins in the 21st Century

    Cyclic Imines and Spirolides

    • Cyclic Imine Toxins: Chemistry, Biogeography, Biosynthesis and Pharmacology
    • Toxicology of Cyclic Imines: Gymnodimine, Spirolides, Pinnatoxins, Pteriatoxins, Prorocentrolide, Spiro-Prorpcentrimine, and Symbiomines

    Polycavernosides: Gambierol

    • Polycavernosides: Gambierol, Chemistry, Pharmacology, Toxicology, and Detection

    Palytoxin, Ostreocin, Ovatatoxin

    • Palytoxin and Analogues: Ecobiology and Origin. Chemistry, Metabolism and Chemical Análisis
    • Diverse Chemical Structures and Bioactivities of Marine Toxin: Palytoxin and Symbiodinolide
    • Palytoxins: Pharmacology and Biological Detection Methods
    • Occurrence and Toxicology of Palytoxins

    Pfiesteria Toxins

    • Pfiesteria spp. Toxins: Unresolved Questions and an Alternative Hypotheses


    • Pharmacology and Epidemiological Impact of Azaspiracids Azaspiracids: Chemistry, Bioconversion and Determination Toxicology of Azaspiracid

    Cyanobacterial Toxins

    • Cyanobacterial Toxins in Aquaculture


    • Cyanobacterial Neurotoxins, Anatoxin-a and Analogues: Detection and Analysis


    • Cyanobacterial Hepatotoxins: Chemistry, Biosynthesis, and Occurrence Hepatotoxins: Context and Chemical Determination

    Toxins as a Starting Point to Drugs

    • Marine Neurotoxins as a Starting Point to Drugs

    Legal and Economical Views

    • Incidence of Marine Toxins on Industrial Activity
    • Toxin Monitoring Programs and Regulatory View


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    Seafood and Freshwater Toxins
    Pharmacology, Physiology, and Detection
    Second edition
    edited by Luis M. Botana

    2008 • 960 pages • $228.95 + shipping
    Texas residents please add 6.75 % sales tax
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