This book is the only available text that assembles the key pieces developers need to produce new breakthroughs for a growing market that demands quicker and more effective results. It also focuses much needed attention on the biochemical and clinical differences between Caucasian and other skin types.

Beginning with detailed descriptions of the forces driving the anti-aging market, this unique book provides readers with all the tools necessary to further research, develop, market, and sell novel products. Recent discoveries on the molecular level and novel methods of skin aging assessment are detailed, as well as the state of the rapidly changing global regulatory environment.

The formulation approaches of major cosmetics companies are presented, as are their techniques for measuring skin aging in vitro and in vivo, both on the molecular and clinical levels.

• Provides philosophical perspective on the growth of the anti-aging market
• Covers skin types beyond Caucasian
• Provides key pieces for developing and selling new breakthrough products
• Includes technology from major cosmetic companies such as Aveda, Estee Lauder, Coty, Avon, and NuSkin

Contents

Long Term Stress and Skin Aging

Part I: Sociological Implications, Market View and IT Frontiers

1. Aging Skin in Socio-cultural Perspective
2. Market Evolution of Topical Anti-aging Treatments
3. Computer Based Age Progression Methodologies

Part II: Biochemical, Pharmacological and Ethnicity Aspects

4. Structural and Biochemical Changes in Aging Skin and Their Implications on Skin Permeability Barrier
5. Changes in Epidermal Lipids and Sebum Secretion with Aging
6. Skin disorders of Inflammation and Immune Suppression in Young and Elder: A Special Role for Mast Cells
7. Cellular Senescence and Skin Aging
8. Prevention and Treatment of Aging Skin with Topical Anti-oxidants
9. Skin Aging in the Asian Population

Part III: Product Development

10. The Use of Natural Compounds and Botanicals in the Development of Anti-aging Skin Care Products
11. Approaches to the Development of Cosmetic Products to Counter Effects of Skin Aging
12. The Design and Development of Anti-aging Skin Care Formulations

Part IV: Testing Methodologies

13. In Vitro Methods to Screen Materials for Anti-aging Effects
14. Clinical Testing to Uphold an Anti-aging Claim

Part V: Regulatory Aspects

15. Cosmetic Anti-aging Formulations - International Regulations
16. Strategic Regulatory Planning - Key to Success in Anti-aging Cosmetic Product Development

Index

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