Skin Moisturization
edited by James J. Leyden

This up-to-date reference:

• Focuses on scientific aspects of moisturization of the skin
• Examines a variety of epidermal conditions and treatments
• Explores all aspects of the consumer moisturization market
• Serves as a useful companion to anyone working with or studying the biology of skin conditions
• Highlights functional changes in the structure of the epidermis and the stratum corneum
• Presents overviews of clinical and comsumer testing approaches together with ex vivo evaluation procedures

Covering key aspect of personal moisturizing and washing products, Skin Moisturization evaluates the:

• Efficacy and formulation of moisturizing ingredients
• Safety and regulatory guidelines involved in the formation of skin-improving technologies
• Development of new products
• Effects of consumer testing approaches

Contents

1. Skin Moisturizer Marketplace

Stratum Corneum and Epidermal Biology

2. Stratum Corneum Ceramides and Their Role in Skin Barrier Function
3. Stratum Corneum Moisturizing Factors
4. Desquamation and the Role of Stratum Corneum Enzymes
5. Cornified Envelope: Its Role in Stratum Corneum Structure and Maturation

Xerotic Skin Conditions

6. Dry and Xerotic Skin Conditions
7. Sensitive Skin and Moisturization
8. Photodamage and Dry Skin
9. Atopic Dermatitis
10. Psoriasis and Ichthyoses
11. Solvent-, Surfactant-, and Tape Stripping-Induced Xerosis

Efficacy of Moisturizers and Moisturizing Ingredients

12. Clinical Effects of Emollients on Skin
13. Humectants
14. Ceramides as Natural Moisturizing Factors and Their Efficacy in Dry Skin
15. Phosphatidylcholine and Skin Hydration
16. Hydroxyacids
17. Salicylic Acid and Derivatives
18. Efficacy, Stability, and Safety of Topically Applied Protease in Treating Xerotic Skin
19. Enzymes in Cleansers
20. Moisturizing Cleaners

Evaluation Methodologies

21. Consumer Testing Methods
22. Clinical Testing of Moisturizers
23. Noninvasive Instrumental Methods for Assesing Moisturizers
24. Laboratory-Based Ex Vivo Assessment of Stratum Corneum Function

Formulation

25. Formulation of Skin Moisturizers
26. Formulation and Assessment of Moisturizing Cleaners

Safety and Regulatory

27. Safety Assessment of Cosmetic Products
28. Regulatory Assessment of Cosmetic Products

Index

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