Stem Cells combines in one volume a body of work encompassing the rapidly advancing developments of stem cell research with a state-of-the-art view of stem cell biology.

Leading experts in the fields of embryonic and adult stem cells have contributed to this book which provides an overview of the important aspects and issues surrounding stem cell research.

Covers:

• molecular mechanisms regulating self-renewal and differentiation of human and mouse ES cells
• adult stem cells, mechanisms and potential applications of these cells in regenerative medicine
• the future of stem cell research

Stem Cells presents in a single volume many novel aspects of stem cell biology with respect to scientific endeavours and future applications. Of particular note is the coverage of the pharmacological issues which have never been adequately addressed in the past.

Contents

• Factors Involved in Self-Renewal and Pluripotency of Embryonic Stem Cells
• Embryonic Stem Cell-Derived Embryoid Bodies: An In Vitro Model of Eutherian Pregastrulation Development and Early Gastrulation
• Embryonic Stem Cells: A Novel Tool for the Study of Antiangiogenesis and Tumor-Induced Angiogenesis
• Cardiac Repair by Embryonic Stem-Derived Cells
• Cardiomyocytes from Human Embryonic Stem Cells
• Autocrine and Intracrine Signaling for Cardiogenesis in Embryonic Stem Cells: A Clue for the Development of Novel Differentiating Agents
• Therapeutic Potential of Stem Cells in Diabetes
• The Stem Cell Continuum: A New Model of Stem Cell Regulation
• Markers of Adult Tissue-Based Stem Cells
• Designer Cytokines for Human Haematopoietic Progenitor Cell Expansion: Impact for Tissue Regeneration
• Mesenchymal Stem Cells: Isolation, In Vitro Expansion and Characterization
• Neovascularization and Cardiac Repair by Bone Marrow-Derived Stem Cells
• The Potential Use of Myogenic Stem Cells in Regenerative Medicine
• Neural Stem Cells: On Where They Hide, in Which Disguise, and How We May Lure Them Out
• Cell Transplantation for Patients with Parkinson’s Disease
• Postmodern Biology: (Adult) (Stem) Cells Are Plastic, Stochastic, Complex, and Uncertain

Index

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