Medical book from C.H.I.P.S.

The Thyroid: A Fundamental and Clinical Text
Ninth Edition
by Lewis E. Braverman

The Thyroid provides comprehensive coverage of every aspect of thyroid anatomy, development, biochemistry, physiology, pathophysiology, and treatment of all thyroid disorders.


The Normal Thyroid

  1. History, Development, Anatomy

  • The Heritage of the Thyroid: A Brief History
  • Development and Anatomy of the Hypothalamic-Pituitary-Thyroid Axis
  • Anatomy and Pathology of the Thyrotrophs

  1. Thyroid Synthesis and Secretion

  • Thyroid Hormone Synthesis
    • Thyroid Iodine Transport
    • Thyroid Hormone Synthesis
  • Thyroglobulin Structure, Function, and Biosynthesis

  1. Peripheral Hormone Metabolism

  • Thyroid Hormone Transport Proteins and the Physiology of Hormone Binding
  • Intracellular Pathways fo Iodothronine Metabolism

  1. Thyroid Hormone Action

  • Genomic and Nongenomic Actions of Thyroid Hormones
  • Thyroid Hormone Structure-Function Relationship

  1. Factors That Control Thyroid Function

  • Thyrotropin
    • Chemistry and Biosynthesis of Thyrotropin
    • The Thrytropin Receptor
    • Biological Actions of Thyrotropin
    • Regulation of Thyrotropin Secretion
  • Intrinsic and Extrinsic Variables
    • Age-Related Changes in Thyroid Secretion
    • Environmental Influences Upon Thyroid Hormone Regulation
    • Effects of Drugs and Othe Substances on Thyroid Hormone Synthesis and Metabolism
    • Nonthyroidal Illness
    • Iodine Deficiency
    • Effect of Excess Iodide: Clinical Aspects

Laboratory Assessment of Thyroid Function

  • In Vivo Radionuclide Tests and Imaging
  • Measuring Serum Thyrotropin and Thyroid Hormone and Assessing Thyroid Hormone Transport
  • Thyroglobulin
  • Thyroid-Directed Antibodies
  • Nonisotpic Techniques of Thyroid Imaging

Introduction to Thyroid Diseases

  • Surgical Anatomy
  • Physical Examination of the Thyroid Gland
  • The Epidemiology of Thyroid Diseases
  • Genetic Factors in Thyroid Dieases
  • Pathology

Thyroid Diseases: Thyrotoxicosis

  1. Introduction
  • Introduction to Thyrotoxicosis

  1. Causes of Hyperthyroidism

  • Graves' Disease
    • Pathogenesis of Graves' Disease
    • Ophthalmopathy
    • Localized Myxedema and Thyroid Acropachy
  • Thyrtropin-Induced Thyrotoxicosis
  • Toxic Adenoma and Toxic Multinodular Goiter
  • Trophoblastic Tumors
  • Sporadic and Postpartum Thyroiditis
  • Subacute Thyroiditis and Acute Infectious Thyroiditis
  • Thyrotoxicosis of Extrathyroid Origin

  1. Organ System Manifestations

  • The Skin in Thyrotoxicosis
  • The Cardiovaslcular System in Thyrotoxicosis
  • The Pulmonary System in Thyrotoxicosis
  • The Kidneys and Electrolyte Metabolism in Thyrotoxicosis
  • The Blood in Thyrotoxicosis
  • The Pituitary in Thyrotoxicosis
  • The Adrenal Cortex in Thyrotoxicosis
  • Thermogenesis and the Sympathoadrenal System in Thyrotoxicosis
  • The Male and Female Reproductive System in Thyrotoxicosis
  • The Skeletal System in Thyrotoxicosis
  • The Neuromuscular System and Brain in Thyrotoxicosis
  • Behavioral and Psychiatric Aspects of Thyrotoxicsis
  • Thyrotoxic Storm

  1. Management of Thyrotoxicosis

  • Diagnosis of Thyrotoxicosis
  • Treatment of Thyrotoxicosis

Thyroid Diseases: Hypothyroidism

  1. Introduction
  • Introduction to Hypothyroidism

  1. Causes of Hypothyroidism
  • Chronic Autoimmune Thyroiditis
  • Genetic Defects Causing Hypothyroidism
  • Endemic Cretinism
  • Primary Hypothyroidism Due to Other Causes
  • Central Hypothyroidism

  1. Organ System Manifestations of Hypothyroidism

  • The Skin and Connective Tissue in Hypothyroidism
  • The Cardiovascular System in Hypothyroidism
  • The Pulmonary System in Hypothyroidism
  • The Kidneys and Electrolyte Metabolism in Hypothyroidism
  • The Gastrointestinal Tract and Liver in Hypothyroidism
  • The Blood in Hypothyroidism
  • The Piuitary in Hypothyroidism
  • The Adrenal Cortex in Hypothyroidism
  • Intermediary Metabolism and the Sympathoadrenal System in Hypothyroidism
  • The Male and Female Reproductive System in Hypothyroidism
  • The Skeletal System in Hypothyroidism
  • The Neuromuscular System and Brain in Hypothyroidism
  • Behavioral and Psychiatric Aspects in Hypothyroidism
  • Myxedema Coma
  1. Management of Hypothyroidism

  • Diagnosis of Hypothyroidism
  • Treatment of Hypothyroidism

Thyroid Diseases: Nontoxic Diffuse And Multinodular Goiter

  • Carcinoma of Follicular Epithelium
    • Epidemiology and Pathogenesis
    • Molecular Genetics of Tumors of Thyroid Follicular Cells
    • Carcinoma of Follicular Epithelium: Surgical Therapy
    • Carcinoma of Follicular Epithelium: Radioiodine and Other Treatments and Outcomes
  • Medullary Thyroid Carcinoma
  • Miscellaneous Tumors of the Thyroid
  • Clinical Evaluations and Management of Solitary Thyroid Nodules

The Thyroid in Infancy and Childhood

  • The Maturation of Thyroid Function in The Perinatal Period and During Childhood
  • Hypothyroidism in Infants and Childern
    • Hypothyroidism in Infants and Childern: Neonatal Screening
    • Hypothyroidism in Infants and Childern: Congenital Hypothyroidism
    • Hypothyroidism in Infants, Childern, and Adolescents: Acquired Hypothyroidism
  • Graves; Disease in the Neonatal Period and Childhood

Special Topics in Thyrodology

  • Morbidity nad Mortality in Thyroid Dysfunction and Its Treatment
  • Subclinical Hypothyroidism
  • Subclinical Thyrotoxicosis
  • Thyroid Disease During Pregnancy
  • Resistance to Thyroid Hormone


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The Thyroid: A Fundamental and Clinical Text
Ninth Edition
by Lewis E. Braverman

2005 1166 pages $258.00 + shipping
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